Protein Alignment Rx and shox2

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_957490.1
• Gene: shox2 / 394171
• ZFINID: ZDB-GENE-040426-1457
• Length: 299
• Species: Danio rerio
• Alignment Length: 326
• Identity: 91/326 - (27%)
• Similarity: 129/326 - (39%)
• Gaps: 97/326 - (29%)

  Fly   491 RNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDL--NQTNSSEQGEKITSGSDDEG---- 549
            |.|.:.:||        .|.:::.:.|.|..|.....|:  ::.:......|:|.|:.|..
Zfish    37 RESLSADPN--------REEISSITRSGVRSSPVREADMLASERSRDSSSPKLTDGNTDMKERKE 93

  Fly   550 -----QDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQN 609
                 :|:...|.|.||:||.||..||:||||.|:::||||.:.||||:.::.|.|.||||||||
Zfish    94 DCKPLEDETQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQN 158

  Fly   610 RRAKWRRQEKSESLRLGLTHFTQLPHRLGCGAS----GLPVDPWLSPPLLSALPGFLSHPQTVYP 670
            ||||.|:||            .||...:..||:    ...|.|:::       .|.|..|.....
Zfish   159 RRAKCRKQE------------NQLHKGVLIGAASQFEACRVAPYVN-------VGALRMPFQQDS 204

  Fly   671 SYLTPPLSL-APGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHV 734
            ....||.|. ....|.:.|..|..|||.|
Zfish   205 HCNVPPFSFQVQAQLQLDSAVAHAHHHLH------------------------------------ 233

  Fly   735 VPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTV-----AVSSSQSSSSSAS 794
               |||:.|...|...|          .|.|.||.:....|::|.:|     |..::..:||.|.
Zfish   234 ---SHLAAHAPYMMFPA----------PPFGLPLATLAAESASAASVVAAAAAAKTTNKNSSIAD 285

  Fly   795 L 795
            |
Zfish   286 L 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	35/55 (64%)
		OAR	876..892	CDD:461067
shox2	NP_957490.1	Homeodomain	109..165	CDD:459649	35/55 (64%)
		OAR	278..295	CDD:461067	4/9 (44%)