Protein Alignment Rx and Vsx2

DIOPT Version :9

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 687
• Identity: 157/687 - (22%)
• Similarity: 220/687 - (32%)
• Gaps: 236/687 - (34%)

  Fly   331 QHLAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINYDERSMSSASDLE 395
            |.|..||..|          |..:||..  ....||...:.:..|..|...|....:.::::...
  Fly    10 QELLGLAVAA----------ATEAPTDL--TTTAGATVAKERQTPTPPKTTNATMATAATSAATA 62

  Fly   396 EDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIRPRSMEEVHH 460
            ....:||:..|...|.|...|:.|                                  ..|:.||
  Fly    63 ATPTNAAEGNLTSVSEPQQQPQQQ----------------------------------QQEQQHH 93

  Fly   461 QQQSHHHQQQQQQQQQQQQLQQQQGF-----------------------QHDFRNSGNGNPNGNS 502
              |.||||.::..|.......:...|                       ||..::..:.:|:
  Fly    94 --QPHHHQYREHHQMTMAAASRMAYFNAHAAVAAAFMPHQLAAAVHHHHQHQHQHHPHHHPH--- 153

  Fly   503 NSGDHG--------------------------------ERLNADSDSLVNGSCA----SSEDLNQ 531
              ..||                                :...|.:.:.:.||.|    ..|.||.
  Fly   154 --HPHGAVGGPPPPPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNG 216

  Fly   532 TNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKV 596
            .......:|              .|||.|.:||.||:|||.:||.||:::||||||:||.|::|.
  Fly   217 FGVGPNSKK--------------KKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKT 267

  Fly   597 NLPEVRVQVWFQNRRAKWRRQEK-----SESLRLGL-----THFTQLPHR-LGCGASGLPVDPWL 650
            .|||.|:||||||||||||:.||     :.....||     .|...||.. |........|.|||
  Fly   268 ELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWL 332

  Fly   651 SPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQ 715
                                      |.:....:...|:.|.......:|........|..
  Fly   333 --------------------------LGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSK---- 367

  Fly   716 PPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSST--- 777
                           |.|...||....|....|..:.::.||.....|  |...:|.||:||
  Fly   368 ---------------SAHSEDLSRSRCHALSSSTESLNVVSPAPSSCP--TSASTSAPPTSTSGY 415

  Fly   778 -------ATTVAVSSSQSSSSSASLECSGPDVCMSP---QNLSIGNADSN------GDGR----- 821
                   |||...:|:.:||||..:|...|    ||   |:|.:......      |.|.
  Fly   416 AGAASSAATTPTGASTTNSSSSPHIELGSP----SPQQQQHLQLQQQQQQQASLYLGAGAVVTGC 476

  Fly   822 ---------DLSSDLDAGSTSSNPG----SSLDKCAASANIELLDVGRDSPPPPPTPTGKG---- 869
                     |.::...||:.:|:..    .:....||:|..:.....:.......|.|..|
  Fly   477 APPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQATATAPGLHAH 541

  Fly   870 ------SSTPPTDMRSNSIATLRIKAKEHLDN-LNKG 899
                  ....|...|:||||.||.||:||... ||.|
  Fly   542 NLAAALMEHDPDAFRNNSIACLRAKAQEHQARLLNNG 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	35/51 (69%)
		OAR	876..892	CDD:281777	9/15 (60%)
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	35/52 (67%)
		OAR	556..570	CDD:281777	9/13 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.920