Protein Alignment Rx and Alx4

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001100023.1
• Gene: Alx4 / 296511
• RGDID: 1310201
• Length: 399
• Species: Rattus norvegicus
• Alignment Length: 649
• Identity: 149/649 - (22%)
• Similarity: 206/649 - (31%)
• Gaps: 302/649 - (46%)

  Fly   262 THHGHAPF-GYHNAFGFG-------QGGHGYGHPEEAAGNYLNSMHQMVEANQLQTGANGANPPP 318
            :..|.:|| |:.....||       ..|.|:|   :|.|.
  Rat    27 SREGSSPFRGFPGGDKFGTTFLSAAAKGQGFG---DAKGR------------------------- 63

  Fly   319 APLPPSSFGSHQQHLAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINY 383
                 :.:|:.||.|||........:...:|:....||   |.|||         ||.||....|
  Rat    64 -----ARYGAGQQDLAAPLESNAGARGSFNKFQPQPPT---PQPPP---------APPAPPAHLY 111

  Fly   384 DERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAG------VFCDDNEPKLANGQ 442
            .:|.             |.|         || |.|.|..:..|.|      |.|...|..|...:
  Rat   112 LQRG-------------ACK---------TP-PDGSLKLQEGSGGHNAALQVPCYAKESNLGEPE 153

  Fly   443 LPGGNYGIRPRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDH 507
            ||       |.|                                          .|.|..||
  Rat   154 LP-------PDS------------------------------------------EPVGMDNS--- 166

  Fly   508 GERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDD----EGQDDNCAKKKHRRNRTTFTT 568
                                .|:...:..:|.:..:|::.    |..|...:|.|.||||||||:
  Rat   167 --------------------YLSVKETGAKGPQDRAGAEIPSPLEKTDSESSKGKKRRNRTTFTS 211

  Fly   569 YQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQL 633
            |||.|||:.|:|:||||||:||:|||:.:|.|.||||||||||||||::|:...::...|||:
  Rat   212 YQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFS-- 274

  Fly   634 PHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAH 698
                                                .:|..|.|:.|.....:.:
  Rat   275 ------------------------------------TAYELPLLTRAENYAQIQN---------- 293

  Fly   699 NGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTP 763
                |..:|:.|...|.|....|...||                  :.|||||
  Rat   294 ----PSWIGNNGAASPVPACVVPCDPVP------------------ACMSPHA------------ 324

  Fly   764 LGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSGPDVCMSPQNLSIGNADSNGDGRDLSSDLD 828
                 |   ||.|.|::|:                        ..||:..|.|:.....:.|..
  Rat   325 -----H---PPGSGASSVS------------------------DFLSVSGAGSHVGQTHMGSLF- 356

  Fly   829 AGSTSSNPGSSLDKCAASANIELLDVGRDSPPPPPTPTGKGSSTPPTDMRSNSIATLRIKAKEH 892
             |:...:||.:               |.:....|             |.:::|||.||:|||||
  Rat   357 -GAAGISPGLN---------------GYEMNGEP-------------DRKTSSIAALRMKAKEH 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	42/55 (76%)
		OAR	876..892	CDD:461067	9/15 (60%)
Alx4	NP_001100023.1	Homeodomain	203..259	CDD:459649	42/55 (76%)
		OAR	375..393	CDD:461067	11/17 (65%)