DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rx and unc-42

DIOPT Version :9

Sequence 1:	NP_726006.3	Gene:	Rx / 37367	FlyBaseID:	FBgn0020617	Length:	904	Species:	Drosophila melanogaster
Sequence 2:	NP_001263845.1	Gene:	unc-42 / 192081	WormBaseID:	WBGene00006778	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	73/250 - (29%)
Similarity:	105/250 - (42%)	Gaps:	70/250 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   475 QQQQQLQQQQGFQHDFRN---------SGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLN 530
            |.|::::......|||..         |.:..|..:.:|....:::..:.   :.||...|....
Worm    17 QFQEKVKDLGVSLHDFTAYYPSSLDTVSASLRPISDPSSDGAFKKIKTEG---LGGSVFGSSIAG 78

  Fly   531 QTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMK 595
            .||:.   .::.|....|.:..|    ..||:|||||..||.||:.||:||||||:|.|||||..
Worm    79 VTNTP---ARLCSLERPESERLN----SRRRHRTTFTQEQLQELDAAFQKSHYPDIYVREELARI 136

  Fly   596 VNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPG 660
            ..|.|.|:||||||||||.|:.||.                         ::..::||     ..
Worm   137 TKLNEARIQVWFQNRRAKHRKHEKQ-------------------------LNKAINPP-----HS 171

  Fly   661 FLSHP------QTVYPSYLT---------------PPLSLAPGNLTMSSLAAMGH 694
            |||:|      |.:||:.|.               |..|.:..|...:.:|..||
Worm   172 FLSNPANTLMRQGMYPAALNRDGFWYQSYQRPMPYPTASPSYSNSFTNPIANFGH 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	36/51 (71%)
Rx	NP_726006.3	OAR	876..892	CDD:281777
unc-42	NP_001263845.1	Homeobox	103..157	CDD:365835	36/53 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910