Protein Alignment Rx and Pitx2

DIOPT Version :9

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 495
• Identity: 114/495 - (23%)
• Similarity: 176/495 - (35%)
• Gaps: 220/495 - (44%)

  Fly   417 RGQLAAKRKSAGV--------FCDDNEPK---LANGQLPGGNYGIRPRSMEEVHHQQQSHHHQQQ 470
            :|.|..:.::||.        ||  :.|:   :|:...||     :|||::...|:.:.|
Mouse     5 KGPLPLEHRAAGTKLSAASSPFC--HHPQALAMASVLAPG-----QPRSLDSSKHRLEVH----- 57

  Fly   471 QQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNSS 535
                                                      ..||:       ||.::.:.:..
Mouse    58 ------------------------------------------TISDT-------SSPEVAEKDKG 73

  Fly   536 EQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPE 600
            :||:     ::|.|.:|...||:.||.||.||:.||.|||..|:::.|||:.:|||:|:..||.|
Mouse    74 QQGK-----NEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTE 133

  Fly   601 VRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHP 665
            .||:|||:|||||||::|:::...|....|       |...:|| :.|:
Mouse   134 ARVRVWFKNRRAKWRKRERNQQAELCKNGF-------GPQFNGL-MQPY---------------- 174

  Fly   666 QTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHG 730
            ..:||.|...  :.|...||.:||:
Mouse   175 DDMYPGYSYN--NWAAKGLTSASLS---------------------------------------- 197

  Fly   731 SHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASL 795
                          ::..|...|:     .|.||.:....| ||:|.       ||.|.|||
Mouse   198 --------------TKSFPFFNSM-----NVNPLSSQSMFS-PPNSI-------SSMSMSSS--- 232

  Fly   796 ECSGPDVCMSPQNLSIGNADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGRDSPP 860
                    |.|                       .:.:..|||||:......|:....:....|.
Mouse   233 --------MVP-----------------------SAVTGVPGSSLNSLNNLNNLSSPSLNSAVPT 266

  Fly   861 P-----PPTPTGKGSSTPP---TDMRSNSIATLRIKAKEH 892
            |     ||        |||   .|..::|:|:||:|||:|
Mouse   267 PACPYAPP--------TPPYVYRDTCNSSLASLRLKAKQH 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	30/51 (59%)
		OAR	876..892	CDD:281777	8/15 (53%)
Pitx2	NP_001035967.1	COG5576	40..>149	CDD:227863	51/172 (30%)
		Homeobox	96..149	CDD:365835	31/52 (60%)
		OAR	282..299	CDD:367680	9/17 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910