Protein Alignment Rx and Dmbx1

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_017175446.1
• Gene: Dmbx1 / 140477
• MGIID: 2153518
• Length: 389
• Species: Mus musculus
• Alignment Length: 476
• Identity: 117/476 - (24%)
• Similarity: 179/476 - (37%)
• Gaps: 130/476 - (27%)

  Fly   447 NYGIRPRSMEEVHHQQQSHH-HQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGER 510
            :||:...|:..::.....:: |||..||.|...          |:|.|        .::....||
Mouse    11 HYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAP----------DYRPS--------VHALTLAER 57

  Fly   511 LNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELE 575
            |         ..|...:.:.:.....|                  .:|.||:||.||..||..||
Mouse    58 L---------AGCTFQDIILEARYGSQ------------------HRKQRRSRTAFTAQQLEALE 95

  Fly   576 RAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKS-ESLRLGLTHFTQLPH---R 636
            :.|:|:|||||..||.|||..||||.||||||:|||||:|::::| :..:|......:..|   :
Mouse    96 KTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGK 160

  Fly   637 LGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGP 701
            :...||...::....|.|.|..|                     |..|.:|    :....|....
Mouse   161 VEAPASDTQLETEQPPGLPSGDP---------------------PAELQLS----LSEQSASESA 200

  Fly   702 PPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGT 766
            |...:......:.:.|.      .....||...|      |...|.||.|.|.||  ..:|| ..
Mouse   201 PEDQLDREEDSRAEEPK------AEKSPGSESKV------PGCKRGSPKADSPGS--LAITP-AA 250

  Fly   767 PLHSSLPPSSTATTVAVS-------------SSQSSSSSASLECSGPDVCMSPQNLSIGNADSNG 818
            |....|.||.:.::..:|             ::.:....:|.|..||    :|...:...|....
Mouse   251 PGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGP----APAAAAAAAAAVPY 311

  Fly   819 DGRDLSSDLDAGSTSSNPGSSLD--------KCAASANIELLDVGRDSPPPPPTPTGKGSSTPPT 875
            .|.:::           |.|||.        ..||:|:..:.    .||..|..|||...::...
Mouse   312 LGVNMA-----------PLSSLHCQSYYQSLSAAAAAHQGVW----GSPLLPAPPTGLAPASAAL 361

  Fly   876 DMRSNSIATLRIKAKEHLDNL 896
            :.::.||..||::||:|..:|
Mouse   362 NSKTTSIENLRLRAKQHAASL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	37/55 (67%)
		OAR	876..892	CDD:461067	6/15 (40%)
Dmbx1	XP_017175446.1	Homeodomain	80..136	CDD:459649	37/55 (67%)