Protein Alignment Rx and LOC1280259

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_061515440.1
• Gene: LOC1280259 / 1280259
• VectorBaseID: AGAMI1_004826
• Length: 650
• Species: Anopheles gambiae
• Alignment Length: 904
• Identity: 172/904 - (19%)
• Similarity: 263/904 - (29%)
• Gaps: 433/904 - (47%)

  Fly   101 NLEQFHEHY---AAHLANNNTV-----------ISTEDS-------NDLVKDNARKYGSGGQTLT 144
            :||..|.|.   |.|...:|.:           .:.||.       .||...||   |||...:.
Mosquito    67 SLEVSHHHRLGPALHPLRSNGLPPGDSEATREEPTNEDEETIDIEITDLSYSNA---GSGSVVVP 128

  Fly   145 PRHTIDAILGLKNRNGAANGSGRNPETVSD-----GSVDPSL----GDDDATDLRCGMT----LT 196
            ...|:.:.:.|| .....:|||.....|.:     |:|:.||    |.::...   |:|    ::
Mosquito   129 EGCTLQSSISLK-PTVVLSGSGGEVTAVGEPNHDKGTVEHSLMLLTGPNNNEK---GVTNRNEIS 189

  Fly   197 QLRSMDNHMASMLQQHAKNGGALPYGPPTPPGGQQPQVPNATPLHHGQQMGGQAGHA-------- 253
            .:|..||..:.:.::                |..|.:..::.....|.:.|||||.|
Mosquito   190 VIRKFDNKRSRVGEE----------------GSVQERSLSSETDEAGVRKGGQAGEAGKRSVGSD 238

  Fly   254 -THAGHGHPTHHGHAPFGY-------------------------HNAFGFGQGGHGYG------- 285
             ...|:|...|..|.|..:                         .:..|..:..|||.
Mosquito   239 GNEGGNGKTIHKRHVPRNWLIADLVDEKKEDKTKDDVALNLVRSESETGPPKQAHGYDPAGLQVV 303

  Fly   286 HPEEAAG------NYLNSMHQMVEANQLQTGANGANPP------------PAPLPPSSFGSHQQH 332
            .|:.|:.      :.:|:.|.......:..|.:....|            |||        .||.
Mosquito   304 RPKPASELLKQSVDLINNHHYSGVVGSIGGGTHSTTVPGTDGESDTEARIPAP--------RQQS 360

  Fly   333 LAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINYDERSMSSASDLEED 397
            |:       .:|:..|..|..:.:.:.|||||
Mosquito   361 LS-------PEQDDPSSSADGTRSDSAPPPPP--------------------------------- 385

  Fly   398 DDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIRPRSMEEVHHQQ 462
                       |:|||...|                                        :.|..
Mosquito   386 -----------TAPPTAEDR----------------------------------------LKHPP 399

  Fly   463 QSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSE 527
            :|..|                         ..||          ||. |:|.|::
Mosquito   400 ESTAH-------------------------VANG----------HGP-LSALSNN---------- 418

  Fly   528 DLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREEL 592
                                          |.||:||.||..||:||||.||::||||.:.||||
Mosquito   419 ------------------------------KQRRSRTNFTLEQLNELERLFEETHYPDAFMREEL 453

  Fly   593 AMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGL---THFTQLPHRLGCGASGLPVDPWLSPPL 654
            :.::.|.|.||||||||||||.|:.|  ..:..|:   :|                     |||:
Mosquito   454 SQRLGLSEARVQVWFQNRRAKCRKHE--NQMHKGIILSSH---------------------SPPV 495

  Fly   655 LSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPP 719
            .:.|     .|..:.|....|.|                  .|..|..||..|.|..|.|
Mosquito   496 TTPL-----EPCRIAPYVNVPSL------------------RAGTGGVPPGSGTGASGLP----- 532

  Fly   720 PPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTVAVS 784
                                                                 |.|||....|.:
Mosquito   533 -----------------------------------------------------PSSSTTAAAAAA 544

  Fly   785 SSQSSSSSASLECSGPDVCMSPQNLSIGNADSNGDGRDLSSDLDAGSTSSN----------PGSS 839
            ::.:::::|::....|....|    :..:|..:...:..::.|.:||..::          || .
Mosquito   545 AAAAAAAAAAVNHPFPVAAFS----AFDSAFISAAAQQYAAALSSGSVPTSLFSLSQYVPRPG-G 604

  Fly   840 LDKCAASANIELLDVGRDSPPPPPTPTGKGSSTPPTDMRSNSIATLRIKAKEHLDNLNK 898
            |...||.|.:....|..|                    :::||..||:||::|.:|..|
Mosquito   605 LAAAAAIATLPGFSVAHD--------------------KNSSIVDLRLKAEKHKENQKK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	36/55 (65%)
		OAR	876..892	CDD:461067	6/15 (40%)
LOC1280259	XP_061515440.1	None