Protein Alignment Rx and dmbx1

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_017949066.1
• Gene: dmbx1 / 100493907
• XenbaseID: XB-GENE-486746
• Length: 367
• Species: Xenopus tropicalis
• Alignment Length: 483
• Identity: 117/483 - (24%)
• Similarity: 169/483 - (34%)
• Gaps: 158/483 - (32%)

  Fly   447 NYGIRPRSMEEVHHQQQSHH-HQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGER 510
            :||:...|:..::.....:: |||..||.|...          |:|.|        .::....||
 Frog     3 HYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAP----------DYRPS--------VHALTLAER 49

  Fly   511 LNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELE 575
            |         ..|...:.:.:.....|                  .:|.||:||.||..||..||
 Frog    50 L---------AGCTFQDIILEARYGSQ------------------HRKQRRSRTAFTAQQLEALE 87

  Fly   576 RAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKS---ESLRL----------GL 627
            :.|:|:|||||..||.|||..||||.||||||:|||||:|::::|   |.|:.          |.
 Frog    88 KTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDSEVSNSEGK 152

  Fly   628 THFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTM-----S 687
            |..|             |.|...|.          ...:..:.|.....:.|   |||:     |
 Frog   153 TEST-------------PADSATSN----------QDSKKAHSSVNDSSVEL---NLTLSEQSAS 191

  Fly   688 SLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHAT 752
            ..||..|......|..|        :.:|.....|.....|.......|.:. ||..|.|:|.::
 Frog   192 ESAAEEHTDKEEEPKTP--------KEEPKTEKNPIADTKPLNCKRASPKTE-SPVSSTMTPSSS 247

  Fly   753 SLGSPHHGV--TPLGT-PLHSSLPPSSTATTVAVS-SSQSSSSSASLECSGPDVCMSP------- 806
            |..:|.|..  :||.. .|.........||...|. ||...:|..::...|.:|.|:|
 Frog   248 SCLTPTHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFDMASPPAVPYLGMNVSMAPLSSLHCQ 312

  Fly   807 ---QNLSIGNADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGRDSPPPPPTPTGK 868
               |:||                 .|....|:|              :|.              .
 Frog   313 SYYQSLS-----------------HAQQVWSSP--------------ILQ--------------S 332

  Fly   869 GSSTPPTDMRSNSIATLRIKAKEHLDNL 896
            ....|..:.::.||..||::||:|..:|
 Frog   333 SGGLPSLNSKTTSIENLRLRAKQHAASL 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	37/55 (67%)
		OAR	876..892	CDD:461067	6/15 (40%)
dmbx1	XP_017949066.1	Homeodomain	72..128	CDD:459649	37/55 (67%)