Protein Alignment Rx and shox2

DIOPT Version :10

• Sequence 1: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001093694.1
• Gene: shox2 / 100101703
• XenbaseID: XB-GENE-480993
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 318
• Identity: 89/318 - (27%)
• Similarity: 132/318 - (41%)
• Gaps: 95/318 - (29%)

  Fly   494 GNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNS----------SEQGEKITSGS-DD 547
            |.|...|....|.....|..|         .|.|.:.::.|          .|:.|::...: ::
 Frog    57 GGGGGGGGGGGGARSPVLELD---------LSVERIRESGSPKLTEVSPEIKERKEELKQQALEE 112

  Fly   548 EGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRA 612
            |||    .|.|.||:||.||..||:||||.|:::||||.:.||||:.::.|.|.|||||||||||
 Frog   113 EGQ----TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRA 173

  Fly   613 KWRRQEKSESLRLGLTHFTQLPHRLGCGA--SGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTP 675
            |.|:||  ..|..|:.        :|.|:  ....|.|:::       .|.|..|.........|
 Frog   174 KCRKQE--NQLHKGVL--------IGAGSQFEACRVAPYVN-------VGALRMPFQQDSHCNVP 221

  Fly   676 PLSL-APGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSH 739
            .||. ....|.:.|..|..|||.                             |||.:.|
 Frog   222 SLSFQVQAQLQLDSAVAHAHHHL-----------------------------HPHLTAH------ 251

  Fly   740 LSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTV--AVSSSQSSSSSASL 795
             :|::...:|             |.|.||.:....::||.:|  |.:::::||.::|:
 Frog   252 -APYMMFPAP-------------PFGLPLATLAAETATAASVVAAAAAAKTSSKNSSI 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	35/55 (64%)
		OAR	876..892	CDD:461067
shox2	NP_001093694.1	Homeodomain	121..177	CDD:459649	35/55 (64%)
		OAR	292..307	CDD:461067	1/4 (25%)