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Protein Alignment CAH15 and CA12

DIOPT Version :9

Sequence 1:	NP_611525.1	Gene:	CAH15 / 37366	FlyBaseID:	FBgn0034560	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001209.1	Gene:	CA12 / 771	HGNCID:	1371	Length:	354	Species:	Homo sapiens

Alignment Length:	278	Identity:	75/278 - (26%)
Similarity:	121/278 - (43%)	Gaps:	36/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LRGSPES--------YNYDWDQGPHTWD---TACNN--QSPINIDMNCVEINYFDTPLIWSHYN- 125
            |:..|.|        :.|....|.::|.   .:|..  ||||::..:.::.:...|||.:..||
Human    17 LKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNL 81

  Fly   126 SIPLGIRLENNGHTLILRAAFPERTPS---IDGGDLLGRFDFREISFRWSWASS-LGSEHTLDHH 186
            |......|.||||::.|      ..||   |.|  |..|:...::...|...:. .|||||:...
Human    82 SANKQFLLTNNGHSVKL------NLPSDMHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQ 138

  Fly   187 HSPLEMQCLHTDG----DGCDGCSSSQGVLMISYMFDLSEHNPFLDVLIQHLAAVEQAGQVVEVP 247
            |...|:..:|.:.    |.....:.|:|:.:::.:.::...||..|.:..||..|:..||...||
Human   139 HFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVP 203

  Fly   248 PFPLSYLMSPFYDKFYSYNGSLTEPPCHRGAEWLIYPESLAISERQLNEFR------QLRDRRGS 306
            .|.:..|:.....::|.|.||||.|||:....|.::...:.||:.||....      .:.|....
Human   204 GFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPR 268

  Fly   307 RIARNARPVQPIGDRMVY 324
            .:..|.|.||...:|:||
Human   269 EMINNFRQVQKFDERLVY 286

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.