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Protein Alignment CAH15 and CA8

DIOPT Version :9

Sequence 1:	NP_611525.1	Gene:	CAH15 / 37366	FlyBaseID:	FBgn0034560	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001308766.1	Gene:	CA8 / 767	HGNCID:	1382	Length:	290	Species:	Homo sapiens

Alignment Length:	279	Identity:	76/279 - (27%)
Similarity:	124/279 - (44%)	Gaps:	53/279 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ESYNYDWDQGPHTW-----DTACNNQSPINIDMNCVEINYFDTPLIWSHYNSIPLGIRLE----- 134
            |...:.:::|.. |     |.....|||||  :|..|..| |..|         |.:||.
Human    25 EGVEWGYEEGVE-WGLVFPDANGEYQSPIN--LNSREARY-DPSL---------LDVRLSPNYVV 76

  Fly   135 -------NNGHTL--ILRAAFPERTPSIDGGDLL--GRFDFREISFRWSWASSLGSEHTLDHHHS 188
                   |:|||:  ||::     ...:.||.|.  ..|:..|:.|.|...:..|||||::....
Human    77 CRDCEVTNDGHTIQVILKS-----KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAF 136

  Fly   189 PLEMQCLHTD----GDGCDGCSSSQGVLMISYMFDLSEHNPFLDVLIQHLAAVEQAGQVVEVPPF 249
            |:|:..:|.:    |...:......|:.:|:....:.:.:..|..:.:.|..::..|:...:|.|
Human   137 PMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201

  Fly   250 -PLSYLMSPFYDKFYSYNGSLTEPPCHRGAEWLIYPESLAISERQLNEFRQLRDR-RGSRIAR-- 310
             |.:.|..|....::.|.||||.|||..|..|:::...|.||:.|:.|||:||.. :|:.:..
Human   202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGC 266

  Fly   311 ------NARPVQPIGDRMV 323
                  |.||.||:.||::
Human   267 DGILGDNFRPTQPLSDRVI 285

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.