Protein Alignment CAH15 and CA4

DIOPT Version :10

• Sequence 1: NP_611525.1
• Gene: CAH15 / 37366
• FlyBaseID: FBgn0034560
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: XP_005257696.1
• Gene: CA4 / 762
• HGNCID: 1375
• Length: 336
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 76/313 - (24%)
• Similarity: 123/313 - (39%)
• Gaps: 78/313 - (24%)

  Fly    65 ANAGGDNCRRLRGSPESYNYDWDQGPHTWDTAC--NNQSPINIDMNCVEINY---------FDTP 118
            |:|....|..::.  ||.||.. ..|..|...|  :.||||||.....:::.         :|..
Human    17 ASAESHWCYEVQA--ESSNYPC-LVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78

  Fly   119 LIWSHYNSIPLGIRLENNGHTLILRAAFPERTPSIDGGDLLGRFDFREISFRWSWASSLGSEHTL 183
            ..|:          ::||||::::   ..|...||.||.|...:..:::...||.....||||:|
Human    79 QTWT----------VQNNGHSVMM---LLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSL 130

  Fly   184 DHHHSPLEMQCLHTDGDGC-----DGCSSSQGVLMISYMFDLSEHN---PFLDV-LIQHLAAVEQ 239
            |..|..:||..:|....|.     :.......:.:::::.::...|   |.... |.|..:...|
Human   131 DGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEIGRMNWPPPLAPCRLSQDPSLPFQ 195

  Fly   240 AG-QVVE-----------VPPFPLSYLMS--------PFYDK---FYSYNGSLTEPPCHRGAEWL 281
            || ||.|           :|...:|..|:        |..:|   ::.|.||||.|.|.....|.
Human   196 AGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWT 260

  Fly   282 IYPESLAISERQLNEFRQ-----------LRDRRGSRIARNARPVQPIGDRMV 323
            ::.|.:.:...|:..|.|           ::|        |.||:|.:|.|.|
Human   261 VFREPIQLHREQILAFSQKLYYDKEQTVSMKD--------NVRPLQQLGQRTV 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH15	NP_611525.1	alpha_CARP_receptor_like	82..325	CDD:239396	71/296 (24%)
CA4	XP_005257696.1	alpha_CA_IV_XV_like	48..307	CDD:239391	66/279 (24%)