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Protein Alignment CAH15 and CA1

DIOPT Version :9

Sequence 1:	NP_611525.1	Gene:	CAH15 / 37366	FlyBaseID:	FBgn0034560	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	262	Identity:	76/262 - (29%)
Similarity:	115/262 - (43%)	Gaps:	23/262 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 SPESYNYDWDQGPHTWDTAC-----NNQSPINIDMNCVEINYFDTPL--IWSHYNSIPLGIR-LE 134
            ||: :.||...||..|....     |||||  :|:...|..: ||.|  |...||  |...: :.
Human     3 SPD-WGYDDKNGPEQWSKLYPIANGNNQSP--VDIKTSETKH-DTSLKPISVSYN--PATAKEII 61

  Fly   135 NNGHTLILRAAFPERTPSIDGGDLLGRFDFREISFRWSWASSLGSEHTLDHHHSPLEMQCLHTD- 198
            |.||:..:.....:....:.||.....:...:..|.|...:..|||||:|......|:...|.:
Human    62 NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNS 126

  Fly   199 ---GDGCDGCSSSQGVLMISYMFDLSEHNPFLDVLIQHLAAVEQAGQVVEVPPFPLSYLMSPFYD 260
               ....:..|.:.|:.:|..:..:.|.||.|..::..|.|::..|:......|..|.|:....|
Human   127 AKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLD 191

  Fly   261 KFYSYNGSLTEPPCHRGAEWLIYPESLAISERQLNEFRQLRDR-RGSR---IARNARPVQPIGDR 321
             |::|.||||.||.:....|:|..||:::|..||.:||.|... .|..   :..|.||.||:..|
Human   192 -FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGR 255

  Fly   322 MV 323
            .|
Human   256 TV 257

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.