DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH15 and ca15a

DIOPT Version :9

Sequence 1:	NP_611525.1	Gene:	CAH15 / 37366	FlyBaseID:	FBgn0034560	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001075158.1	Gene:	ca15a / 553469	ZFINID:	ZDB-GENE-070424-7	Length:	324	Species:	Danio rerio

Alignment Length:	293	Identity:	65/293 - (22%)
Similarity:	115/293 - (39%)	Gaps:	96/293 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 WDQ-GPHTWDTACN--NQSPINI-------DMNCVEINY--FDTPLIWSHYNSIPLGIRLENNGH 138
            |.: .||    .||  :||||||       :.|..:.|:  ||....:         |.:.|:|.
Zfish    38 WPELSPH----YCNGSSQSPINIVTAQVLENSNLTQFNFTGFDANTTF---------ISMANSGI 89

  Fly   139 TLILRAAFPERTPSIDGGDLLGRFDFREISFRWSWASSL-GSEHTLDHHHSPLEMQCLHTDG--- 199
            ::::  ...|...|:.||||.|.:..::....|..:||. |||||:|.....:|:..::...
Zfish    90 SVVV--TLDEEIMSVQGGDLPGLYVSKQFHLHWGNSSSFPGSEHTVDGKQYAMELHIVNVHSKYN 152

  Fly   200 ----------------------DGCDGCSSSQG-VLMISYMFDLS-EHNPFLDVLIQH-----LA 235
                                  :|.:..|.::| .::.|::.::: ..|..:|::.:.     |.
Zfish   153 GSLSAALAANDSSALAVLGFFIEGTNEASKAKGWGVLTSFLRNITYSGNATVDIMNRTSMNSLLE 217

  Fly   236 AVEQAGQVVEVPPFPLSYLMSPFYDKFYSYNGSLTEPPCHRGAEWLIYPESLAISERQLNEFRQL 300
            .|.:.                    |:|.|.||||.|.|:....|.::.|.:.::...:|.|..
Zfish   218 GVNKT--------------------KYYRYRGSLTTPSCNEAVIWTVFKEPIKVNNNLINLFST- 261

  Fly   301 RDRRGSRIARNA----------RPVQPIGDRMV 323
                 :..|:||          |.|||:..|:|
Zfish   262 -----TVFAKNASAPVLNVNNFRGVQPLNGRVV 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH15	NP_611525.1	alpha_CARP_receptor_like	82..325	CDD:239396	65/293 (22%)
ca15a	NP_001075158.1	alpha_CA_IV_XV_like	48..291	CDD:239391	60/279 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850