DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH15 and Ptprg

DIOPT Version :9

Sequence 1:	NP_611525.1	Gene:	CAH15 / 37366	FlyBaseID:	FBgn0034560	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	86/330 - (26%)
Similarity:	141/330 - (42%)	Gaps:	63/330 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SNLLKFILAIGVALLVLFNVYTGFSLANRCDEGSNDGCANAGGDNCRRLRGSPESY-NYDWDQGP 90
            |::|.::    |....|...|.|....:|  :||:        ...||.:.|.:.| .|....||
  Rat    18 SSVLHYV----VCFPALTEGYVGTLQESR--QGSS--------VQIRRRKASGDPYWAYSGAYGP 68

  Fly    91 HTWDT---AC--NNQSPINI---------DMNCVEINYFD---TPLIWSHYNSIPLGIRLENNGH 138
            ..|.|   :|  ::||||:|         :...::::.||   :...|           ::|.|.
  Rat    69 EHWVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTW-----------MKNTGK 122

  Fly   139 T--LILRAAFPERTPSIDGGDLLGRFDFREISFRWSWAS-SLGSEHTLDHHHSPLEMQCLHTDGD 200
            |  ::|:..:     .:.|..|.|||...::.|.|..:: |.||||:::....|:|||....:.|
  Rat   123 TVAILLKDDY-----FVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPD 182

  Fly   201 GCD----GCSSSQGVLMISYMFDLS-EHNPFLDVLIQHLAAVEQAGQVVEVPPFPLSYLMSPFYD 260
            ..|    ..|.::.:..::..|.:| ..|..||.:|..|..|....:...:.||.|..|:.....
  Rat   183 DFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLG 247

  Fly   261 KFYSYNGSLTEPPCHRGAEWLIYPESLAISERQLNEF-------RQLRDRRGSRIARNARPVQPI 318
            .:|.|.||||.|||....||:::...:.||..||..|       :|...:....:..|.||.|.:
  Rat   248 SYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQAL 312

  Fly   319 GDRMV 323
            .||:|
  Rat   313 NDRVV 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH15	NP_611525.1	alpha_CARP_receptor_like	82..325	CDD:239396	74/275 (27%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	72/267 (27%)
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810