Protein Alignment otp and OTX2

DIOPT Version :9

• Sequence 1: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001257454.1
• Gene: OTX2 / 5015
• HGNCID: 8522
• Length: 297
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 73/225 - (32%)
• Similarity: 105/225 - (46%)
• Gaps: 45/225 - (20%)

  Fly   115 KQKRHRTRFTPAQLNELERCFSKTHYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKR----- 174
            ||:|.||.||.|||:.||..|:||.|||||||||:|::|.|.||||||||:|||||.:::
Human    45 KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ 109

  Fly   175 ----------KKTTNVFRTPGALLPSHG--LPPFGANITNIAMGDGLCGTGMFGGDRWSVG---- 223
                      ||.|:..|...:...:.|  .||...::..||........       ||..
Human   110 NGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSI-------WSPASISP 167

  Fly   224 -VNPMTAGFGQLNQSSPLSSSLNSGLNSGINMGSALGAGSYQHYGLNALGD---SMMYQHSVGGV 284
             .:|::.....:.:|.|::.:..||.:.|.       |||..::|....|.   .|.:|....|.
Human   168 LSDPLSTSSSCMQRSYPMTYTQASGYSQGY-------AGSTSYFGGMDCGSYLTPMHHQLPGPGA 225

  Fly   285 SCGPSGSPSATTPPNMNSCSSVTPPPLSAQ 314
            :..|.|:.:.|:..|.      :|..||.|
Human   226 TLSPMGTNAVTSHLNQ------SPASLSTQ 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	32/47 (68%)
OTX2	NP_001257454.1	Homeobox	50..102	CDD:395001	37/51 (73%)
		TF_Otx	163..242	CDD:397546	18/91 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I5000
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960