Protein Alignment otp and Pitx1

DIOPT Version :9

• Sequence 1: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_035227.1
• Gene: Pitx1 / 18740
• MGIID: 107374
• Length: 315
• Species: Mus musculus
• Alignment Length: 257
• Identity: 85/257 - (33%)
• Similarity: 126/257 - (49%)
• Gaps: 48/257 - (18%)

  Fly    80 NGGNGSSGNGNGNNNNGNGNNNNSMQQQDQHLDKNKQKRHRTRFTPAQLNELERCFSKTHYPDIF 144
            :||.||:|.|.|               .:....|.||:|.||.||..||.|||..|.:..|||:.
Mouse    69 DGGAGSAGCGGG---------------AEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMS 118

  Fly   145 MREEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHG--LPPFGANITNIAMGD 207
            ||||||:...|||.||:|||:||||||:||::...:....|..:|...  :.|:          :
Mouse   119 MREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPY----------E 173

  Fly   208 GLCGTGMFGGDRW---SVGVNPM-TAGFGQLNQSSPLSS----SLNSGLNSGINMGSALGAGS-- 262
            .:...| :..:.|   |:...|: |..|...|..|||||    |..|.::| :.|.|::|.|:
Mouse   174 DVYAAG-YSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISS-MTMPSSMGPGAVP 236

  Fly   263 -YQHYGLNAL----GDSMMYQHSVGGVSCGPSGSPSATTPPNMNSC-SSVTPPPLSAQPNSS 318
             ..:.|||.:    |.|:....|.|  :| |.|:|::......::| ||:....|.::.:||
Mouse   237 GMPNSGLNNINNLTGSSLNSAMSPG--AC-PYGTPASPYSVYRDTCNSSLASLRLKSKQHSS 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	27/47 (57%)
Pitx1	NP_035227.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		17/49 (35%)
		Homeobox	94..147	CDD:365835	33/52 (63%)
		Interaction with PIT-1	151..280		33/143 (23%)
		Forkhead_N	196..>275	CDD:369872	26/82 (32%)
		OAR	277..294	CDD:367680	4/16 (25%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	281..294		3/12 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	287..291		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I5012
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960