Protein Alignment otp and Pitx1

DIOPT Version :9

• Sequence 1: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_446076.1
• Gene: Pitx1 / 113983
• RGDID: 69253
• Length: 315
• Species: Rattus norvegicus
• Alignment Length: 257
• Identity: 84/257 - (32%)
• Similarity: 125/257 - (48%)
• Gaps: 48/257 - (18%)

  Fly    80 NGGNGSSGNGNGNNNNGNGNNNNSMQQQDQHLDKNKQKRHRTRFTPAQLNELERCFSKTHYPDIF 144
            :||.||:|.|:.                :....|.||:|.||.||..||.|||..|.:..|||:.
  Rat    69 DGGAGSAGCGSA----------------EDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMS 117

  Fly   145 MREEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHG--LPPFGANITNIAMGD 207
            ||||||:...|||.||:|||:||||||:||::...:....|..:|...  :.|:          :
  Rat   118 MREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPY----------E 172

  Fly   208 GLCGTGMFGGDRW---SVGVNPM-TAGFGQLNQSSPLSS----SLNSGLNSGINMGSALGAGS-- 262
            .:.....:..:.|   |:...|: |..|...|..|||||    |..|.::| :.|.|::|.||
  Rat   173 DVYAAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISS-MTMPSSMGPGSVP 236

  Fly   263 -YQHYGLNAL----GDSMMYQHSVGGVSCGPSGSPSATTPPNMNSC-SSVTPPPLSAQPNSS 318
             ..:.|||.:    |.|:....|.|  :| |.|:|::......::| ||:....|.::.:||
  Rat   237 GMPNSGLNNINNLTGSSLNSAMSPG--AC-PYGTPASPYSVYRDTCNSSLASLRLKSKQHSS 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	27/47 (57%)
Pitx1	NP_446076.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		16/49 (33%)
		Homeobox	93..146	CDD:395001	33/52 (63%)
		Interaction with PIT-1. /evidence=ECO:0000250	149..280		33/144 (23%)
		OAR	277..294	CDD:397759	4/16 (25%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	281..294		3/12 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	287..291		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I4895
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960