DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cib2 and cib2

DIOPT Version :9

Sequence 1:	NP_611523.3	Gene:	Cib2 / 37363	FlyBaseID:	FBgn0034558	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_957000.1	Gene:	cib2 / 393679	ZFINID:	ZDB-GENE-040426-1663	Length:	187	Species:	Danio rerio

Alignment Length:	189	Identity:	117/189 - (61%)
Similarity:	137/189 - (72%)	Gaps:	2/189 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKVVTFTEQELDDYQDCTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASSVKVPCECIEKMP 65
            ||||...||:::||.||||||||||||||:|.|:.||.|.|||...|..  ..||||...|..||
Zfish     1 MGNKQTIFTDEQLDAYQDCTFFTRKEILRLHGRYHELAPHLVPMDYTND--PDVKVPLALIVNMP 63

  Fly    66 ELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYDFDQDGFIGHADL 130
            ||:|||||.||.|:||.||||||||.||:|..||.||.|||::|..||||||||:.|.:|...||
Zfish    64 ELKENPFRNRIVESFSEDGQGNLSFNDFVDMFSVLSEMAPRELKAIYAFKIYDFNVDNYICKEDL 128

  Fly   131 MSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEFEHVILRAPDFLSTFHIRI 189
            ...|..:||.||:|||...:.:|.|||||:|||.|||..:||::|.|||||||||||||
Zfish   129 EKTLNKLTKEELTPEEVNLVCEKAIEEADLDGDNKLSFADFENMISRAPDFLSTFHIRI 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cib2	NP_611523.3	FRQ1	20..180	CDD:227455	94/159 (59%)
cib2	NP_957000.1	EFh	107..174	CDD:238008	35/66 (53%)
cib2	NP_957000.1	EF-hand_7	111..173	CDD:290234	33/61 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592186
Domainoid	1	1.000	138	1.000	Domainoid score	I4807
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4653
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3370
OMA	1	1.010	-	-		QHG52608
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	1	1.000	-	-		FOG0002598
OrthoInspector	1	1.000	-	-		otm26120
orthoMCL	1	0.900	-	-		OOG6_106257
Panther	1	1.100	-	-	O	PTHR45791
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4133
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940