DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cib2 and Ppp3r2

DIOPT Version :9

Sequence 1:	NP_611523.3	Gene:	Cib2 / 37363	FlyBaseID:	FBgn0034558	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001004025.1	Gene:	Ppp3r2 / 19059	MGIID:	107171	Length:	179	Species:	Mus musculus

Alignment Length:	175	Identity:	62/175 - (35%)
Similarity:	92/175 - (52%)	Gaps:	18/175 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKVVTFTEQELDDYQDCTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASSVKVPCECIEKMP 65
            |||:....||.       |..|.::||.|:.|.||:|..|         ::.|:.:  |...::|
Mouse     1 MGNEASYQTEL-------CNHFDQEEIRRLGKSFRKLDLD---------KSGSLSI--EEFMRLP 47

  Fly    66 ELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYDFDQDGFIGHADL 130
            ||::||...|:.:.|..||.|.:.|.:|:...|.||.:...:.|:.:||:|||.|.||||.:.:|
Mouse    48 ELQQNPLVGRVIDIFDTDGNGEVDFHEFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGEL 112

  Fly   131 MSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEFEHVI 175
            ...|..|..|.|...:.||:.||.|...|.||||::|..||..|:
Mouse   113 FQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFSDVV 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cib2	NP_611523.3	FRQ1	20..180	CDD:227455	56/156 (36%)
Ppp3r2	NP_001004025.1	PTZ00184	17..153	CDD:185504	52/146 (36%)
		EFh	25..76	CDD:238008	18/61 (30%)
		EFh	91..158	CDD:238008	30/67 (45%)
		Calcineurin A binding. /evidence=ECO:0000250\|UniProtKB:Q63810	131..136		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850