DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cib2 and calm-1

DIOPT Version :9

Sequence 1:	NP_611523.3	Gene:	Cib2 / 37363	FlyBaseID:	FBgn0034558	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_492514.2	Gene:	calm-1 / 172774	WormBaseID:	WBGene00009260	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	106/201 - (52%)
Similarity:	141/201 - (70%)	Gaps:	12/201 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGN------------KVVTFTEQELDDYQDCTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASS 53
            |||            |...||.::||:||||||||||:|:|::|||..|.|..||..|...:.:.
Worm     1 MGNNASSLSELNLFSKGGVFTREQLDEYQDCTFFTRKDIIRLYKRFYALNPHKVPTNMQGNRPAI 65

  Fly    54 VKVPCECIEKMPELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYD 118
            ..:..|.:||||||:||||:|||||.||.||:|||||:||||..|||||.||..:|:.|||:|||
Worm    66 TTLTFEEVEKMPELKENPFKRRICEVFSEDGRGNLSFDDFLDMFSVFSEMAPLQLKLKYAFRIYD 130

  Fly   119 FDQDGFIGHADLMSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEFEHVILRAPDFLS 183
            :|.|..:||.||...:.::|::|||..|.:.|.:::|||||:|||..::..|||||:.|:|||:.
Worm   131 YDGDELLGHDDLSKMIRSLTRDELSDVEVEFIIERIIEEADLDGDSSINFAEFEHVVSRSPDFIR 195

  Fly   184 TFHIRI 189
            ||||||
Worm   196 TFHIRI 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cib2	NP_611523.3	FRQ1	20..180	CDD:227455	85/159 (53%)
calm-1	NP_492514.2	FRQ1	32..192	CDD:227455	85/159 (53%)
calm-1	NP_492514.2	EFh	121..183	CDD:298682	27/61 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157896
Domainoid	1	1.000	131	1.000	Domainoid score	I3222
eggNOG	1	0.900	-	-		E2759_KOG0038
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4653
Inparanoid	1	1.050	222	1.000	Inparanoid score	I2272
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52608
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	1	1.000	-	-		FOG0002598
OrthoInspector	1	1.000	-	-		oto19853
orthoMCL	1	0.900	-	-		OOG6_106257
Panther	1	1.100	-	-	LDO	PTHR45791
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4133
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800