DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KCNA1 and RPL37B

DIOPT Version :10

Sequence 1:NP_000208.2 Gene:KCNA1 / 3736 HGNCID:6218 Length:495 Species:Homo sapiens
Sequence 2:NP_010788.1 Gene:RPL37B / 852111 SGDID:S000002908 Length:88 Species:Saccharomyces cerevisiae


Alignment Length:56 Identity:15/56 - (26%)
Similarity:19/56 - (33%) Gaps:15/56 - (26%)


- Green bases have known domain annotations that are detailed below.


Human    17 GHPQDGSYPRQADHDDHECCERVVINISGLR-FETQLKTLAQFPNTLLGNPKKRMR 71
            |.|..|    :..:..|..|.|     .|.| |..|.||.:.     .|.|..:.|
Yeast     4 GTPSFG----KRHNKSHTLCNR-----CGRRSFHVQKKTCSS-----CGYPSAKTR 45

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KCNA1NP_000208.2 Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P10499 1..128 15/56 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30 3/12 (25%)
BTB_POZ 37..163 CDD:453885 10/36 (28%)
Ion_trans 166..418 CDD:459842
S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 310..323
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 372..377
PDZ-binding. /evidence=ECO:0000250 493..495
RPL37BNP_010788.1 PTZ00073 1..83 CDD:240257 15/56 (27%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.