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Protein Alignment CAH14 and CA3

DIOPT Version :9

Sequence 1:	NP_611519.2	Gene:	CAH14 / 37359	FlyBaseID:	FBgn0034554	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_005172.1	Gene:	CA3 / 761	HGNCID:	1374	Length:	260	Species:	Homo sapiens

Alignment Length:	249	Identity:	58/249 - (23%)
Similarity:	92/249 - (36%)	Gaps:	30/249 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NAVGNRRLEMKLAKQPSPITIPESNMIKRQLKMPLHWTYYEDLPMATVLENNGNTVIMRIYTANN 122
            ||.|..:         ||:.:...::.......|  |:...|...|..:.|||.|  .|:...:.
Human    22 NAKGENQ---------SPVELHTKDIRHDPSLQP--WSVSYDGGSAKTILNNGKT--CRVVFDDT 73

  Fly   123 F-MPQLSGAELLGRYQFVEAIFKWGSLK---SEHSIGKHNFCLELQALHRCAQLNNNFEYL---- 179
            : ...|.|..|.|.|:..:....|||..   |||::....:..||..:|...:.|...|.|
Human    74 YDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRD 138

  Fly   180 ---TLSYLFALSHVKNEHLKQVTDHLKWISQPGSSIELPPFHLESLLQPFGSGYFSYEGTYDNGD 241
               .:.....:.| :|...:...|.|..|...|.......|. .|.|.|....|::|:|::....
Human   139 GIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPFTKFD-PSCLFPACRDYWTYQGSFTTPP 201

  Fly   242 VVLPTTWLINRKISVVDSRQLSEFEALYGRNGNRN----CKNGREKQPLGNRNV 291
            ......||:.::...|.|.|:::..:|.....|..    ..|.|..||:.||.|
Human   202 CEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVV 255

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.