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Protein Alignment CAH14 and CA1

DIOPT Version :9

Sequence 1:	NP_611519.2	Gene:	CAH14 / 37359	FlyBaseID:	FBgn0034554	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	239	Identity:	61/239 - (25%)
Similarity:	95/239 - (39%)	Gaps:	32/239 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 SPITIPESNMIKRQLKMPLHWTYYEDLPMATVLE--NNGNTVIMRIYTANNFMPQLSGAELLGRY 136
            ||:.|..|.........|:..:|..    ||..|  |.|::..:. :..|:....|.|......|
Human    30 SPVDIKTSETKHDTSLKPISVSYNP----ATAKEIINVGHSFHVN-FEDNDNRSVLKGGPFSDSY 89

  Fly   137 QFVEAIFKWGSLK---SEHSIGKHNFCLELQALHRCAQLNNNFEYLT----------LSYLFALS 188
            :..:..|.|||..   |||::....:..||...|.     |:.:|.:          |:.:..|.
Human    90 RLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHW-----NSAKYSSLAEAASKADGLAVIGVLM 149

  Fly   189 HV--KNEHLKQVTDHLKWISQPGSSIELPPFHLESLLQPFGSGYFSYEGTYDNGDVVLPTTWLIN 251
            .|  .|..|::|.|.|:.|...|.......|...:|| |....:::|.|:..:..:....||:|.
Human   150 KVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLL-PSSLDFWTYPGSLTHPPLYESVTWIIC 213

  Fly   252 RKISVVDSRQLSEFEALY----GRNGNRNCKNGREKQPLGNRNV 291
            ::...|.|.||::|.:|.    |.|......|.|..|||..|.|
Human   214 KESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTV 257

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.