Protein Alignment CAH14 and PTPRG

DIOPT Version :10

• Sequence 1: NP_611519.2
• Gene: CAH14 / 37359
• FlyBaseID: FBgn0034554
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: XP_016862450.1
• Gene: PTPRG / 5793
• HGNCID: 9671
• Length: 1485
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 54/263 - (20%)
• Similarity: 87/263 - (33%)
• Gaps: 72/263 - (27%)

  Fly    97 YEDLPM---------ATVLENNGNTVIMRIYTANNFMPQLSGAELLGRYQFVEAIFKW----GSL 148
            |::|.:         .|.::|.|.||  .|...:::.  :|||.|.||::..:..|.|    ||.
Human    99 YQELQLDGFDNESSNKTWMKNTGKTV--AILLKDDYF--VSGAGLPGRFKAEKVEFHWGHSNGSA 159

  Fly   149 KSEHSIGKHNFCLELQALHR---CAQLNNNFEYLTL----------------------------- 181
            .|||||....|.:|.:....   ...|:....::.|
Human   160 GSEHSINGRRFPVEAEDARGGDIMLMLSQGMRFILLGLKKEQFEERKSWTTYQSMQIFFYNPDDF 224

  Fly   182 ----------------SYLFALSHVKNEHLKQVTDHLKWISQPGSSIELPPFHLESLLQPFGSGY 230
                            :..|.:|...|..|..:...||.:........|.||.|..||......|
Human   225 DSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSY 289

  Fly   231 FSYEGTYDNGDVVLPTTWLINRKISVVDSRQLSEFEALYGRNGNRNCK-------NGREKQPLGN 288
            :.|.|:...........|::.|:...:...||..|.:::......:.|       |.|.:|.|.:
Human   290 YRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHD 354

  Fly   289 RNV 291
            |.|
Human   355 RVV 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH14	NP_611519.2	alpha_CARP_receptor_like	69..293	CDD:239396	54/263 (21%)
PTPRG	XP_016862450.1	alpha_CARP_receptor_like	67..359	CDD:239396	54/263 (21%)
		FN3	388..478	CDD:238020
		PHA03169	<584..>742	CDD:223003
		R-PTPc-G-1	888..1161	CDD:350505
		R-PTP-G-2	1245..1449	CDD:350508