DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH14 and cah-3

DIOPT Version :9

Sequence 1:	NP_611519.2	Gene:	CAH14 / 37359	FlyBaseID:	FBgn0034554	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001370788.1	Gene:	cah-3 / 181713	WormBaseID:	WBGene00000281	Length:	246	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	85/221 - (38%)	Gaps:	8/221 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 SPITIPESNMIKRQLKMPLHWTYYEDLPMATVLENNGNTVIMRIYTANNFMPQLSGAELLGRYQF 138
            |||.|....:.::.....:.:..| |.|:...:.|||::|.|.....:.. |::.|..|...|:.
Worm    25 SPINIDLGEVERKDTHDGIKFVNY-DHPIQGDIVNNGHSVQMTPELRSEH-PEIYGGGLDQVYRL 87

  Fly   139 VEAIFKWG---SLKSEHSIGKHNFCLELQALHRCAQLNNNFEYLTLSYLFALSHVKNEHLKQVTD 200
            |:..|.||   :..|||::|...:..||..:|:..:....   |.:..:|.....:.:.|.....
Worm    88 VQYHFHWGENDNEGSEHTLGGLRYPAELHLVHQGVEDPGK---LAVVGVFLQLGKEGKALSNEER 149

  Fly   201 HLKWISQPGSSIELPPFHLESLLQPFGSGYFSYEGTYDNGDVVLPTTWLINRKISVVDSRQLSEF 265
            .|..:..|.:...:....|...|......::.|||:..........||.|..:...|...||..|
Worm   150 VLGKLCNPETVTRVENVRLSEKLPANKRSFWRYEGSLTTPPCSEIVTWTIFTEPVTVTHDQLELF 214

  Fly   266 EALYGRNGNRNCKNGREKQPLGNRNV 291
            ..:.........||.|..|.|.:|.:
Worm   215 RQVQDIEKRPIKKNYRPTQNLNDRKI 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH14	NP_611519.2	alpha_CARP_receptor_like	69..293	CDD:239396	50/221 (23%)
cah-3	NP_001370788.1	Carb_anhydrase	5..239	CDD:215000	49/218 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020