DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH14 and Ptprg

DIOPT Version :9

Sequence 1:	NP_611519.2	Gene:	CAH14 / 37359	FlyBaseID:	FBgn0034554	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	223	Identity:	53/223 - (23%)
Similarity:	88/223 - (39%)	Gaps:	32/223 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 YEDLPM---------ATVLENNGNTVIMRIYTANNFMPQLSGAELLGRYQFVEAIFKW----GSL 148
            |::|.:         .|.::|.|.||  .|...:::.  :|||.|.||::..:..|.|    ||.
  Rat    99 YQELQLDGFDNESSNKTWMKNTGKTV--AILLKDDYF--VSGAGLPGRFKAEKVEFHWGHSNGSA 159

  Fly   149 KSEHSIGKHNFCLELQALHRCAQLNNNFEYL--------TLSYLFALSHVKNEHLKQVTDHLKWI 205
            .||||:....|.:|:|.........::|:..        .::..|.:|...|..|..:...||.:
  Rat   160 GSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGV 224

  Fly   206 SQPGSSIELPPFHLESLLQPFGSGYFSYEGTYDNGDVVLPTTWLINRKISVVDSRQLSEFEALYG 270
            ........|.||.|..||......|:.|.|:...........|::.|:...:...||..|.:::.
  Rat   225 VHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFT 289

  Fly   271 RNGNRNCK-------NGREKQPLGNRNV 291
            .....:.|       |.|.:|.|.:|.|
  Rat   290 TEQQDHVKSVEYLRNNFRPQQALNDRVV 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH14	NP_611519.2	alpha_CARP_receptor_like	69..293	CDD:239396	53/223 (24%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	53/223 (24%)
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910