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Protein Alignment CAH14 and CA5B

DIOPT Version :9

Sequence 1:	NP_611519.2	Gene:	CAH14 / 37359	FlyBaseID:	FBgn0034554	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_009151.1	Gene:	CA5B / 11238	HGNCID:	1378	Length:	317	Species:	Homo sapiens

Alignment Length:	311	Identity:	78/311 - (25%)
Similarity:	116/311 - (37%)	Gaps:	63/311 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LCWLKFIRAFGLVMQLAEESRFI----MMLISCTMAVAFILNLYSGRT-----IFQDVVNAVGNR 63
            |.|.||           :..||:    ..|.:||         |..|.     :::.|....|..
Human    18 LLWRKF-----------QIPRFMPARPCSLYTCT---------YKTRNRALHPLWESVDLVPGGD 62

  Fly    64 RLEMKLAKQPSPITIPESNMIKRQLKMPLHWTYYEDLPMATVLE--NNGNTVIMRIYTANNFMPQ 126
            |        .|||.|...:.:......||..:|    ..||.|.  |||.:.::....:.: ...
Human    63 R--------QSPINIRWRDSVYDPGLKPLTISY----DPATCLHVWNNGYSFLVEFEDSTD-KSV 114

  Fly   127 LSGAELLGRYQFVEAIFKWGSLK---SEHSIGKHNFCLELQALHRCAQLNNNFEYLTLS------ 182
            :.|..|...|:..:..|.||::.   |||::....|..||..:|..|....|||...|.
Human   115 IKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAV 179

  Fly   183 ---YLFALSHVKNEHLKQVTDHLKWISQPGSSIELPPFHLESLLQPFGSGYFSYEGTYDNGDVVL 244
               :|....|  ::.|:::.|.|..|....:.:|...|. .|.|.|....|::|.|:.....:..
Human   180 IGVFLKLGKH--HKELQKLVDTLPSIKHKDALVEFGSFD-PSCLMPTCPDYWTYSGSLTTPPLSE 241

  Fly   245 PTTWLINRKISVVDSRQLSEFEALY----GRNGNRNCKNGREKQPLGNRNV 291
            ..||:|.::...||..||.:|..|.    |....|...|.|..|||.||.|
Human   242 SVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTV 292

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.