DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9993 and ACOS5

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_176482.1	Gene:	ACOS5 / 842596	AraportID:	AT1G62940	Length:	542	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	158/565 - (27%)
Similarity:	252/565 - (44%)	Gaps:	92/565 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KDKEYYG---------PD-MTLGEVALIILRLYSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQ 71
            :|.||..         || :||.|..|..:..|::.|..|...||:.:|...::..::|||.|..
plant     7 EDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEYTENVAFVEAVTGKAVTYGDVVRDTKRLAKALT 71

  Fly    72 RLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFEITK------PKVIF 130
            .|.|::|.|:.:...|......:.:..:..|...:..:|      ||.:.||.|      .:.|.
plant    72 SLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANP------TALVSEIKKQVEASGARGII 130

  Fly   131 CDLDNYQTLSAVKSSLKFKTEIILLTGTLPGVRNIQDLLADGCTGYDEKTLFACPHLCGD----- 190
            .|..||:.:.::...:     |:|....:.|..|.:|||..|     :|        |||
plant   131 TDATNYEKVKSLGLPV-----IVLGEEKIEGAVNWKDLLEAG-----DK--------CGDTDNEE 177

  Fly   191 ----DTAFIITSSGVTGLPKGVTRSHRSLL----------NSAKIPQLFTSDTVLFCFSPLYWIS 241
                |...:..|||.|||.|||..:||:|:          .|..|.|:.|...:     |.:.|.
plant   178 ILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSTLFGVRSEMIGQIVTLGLI-----PFFHIY 237

  Fly   242 CIFTLLASLVNGCRRIITNRPFSVAYFADLVERHQVSFVLTVPHHMALLAKSPERQELAAKMQCV 306
            .|..:..:.:....:::....:.:..|.:.:..|:|||...||..:..|.|:|...|.......:
plant   238 GIVGICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKL 302

  Fly   307 QSFVCSGSKVPMGIWRQLYELLGA--NRFAVL-----YGLTETGGISKNVGGP--------LGSE 356
            ||.:.:.:.:..       |||.|  .:|..:     |||||...|:...|.|        ..|.
plant   303 QSVMTAAAPLAP-------ELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSV 360

  Fly   357 GRLLRNVQVRVVDPH-GQSLGPNQTGQILVRLNLRWGGYYHNPQETQVTVTPDGKWLLTGDHGYF 420
            |.:|.|::|:.:||. |:||..|.:|::.||......||:.|.:||..|:...| ||.|||.||.
plant   361 GFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFMNKEETDKTIDEQG-WLHTGDIGYI 424

  Fly   421 DDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAVVRNEDE 485
            ||:|.:....|..::.||..|.:.|.::|.::|..|.|.:|||..:|||.:..:.|..||.|..
plant   425 DDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPK- 488

  Fly   486 LGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRR 530
              |...|.|:...||.:::....:| .|.|||::||:.:.|:.||
plant   489 --ATEKEEDILNFVAANVAHYKKVR-AVHFVDSIPKSLSGKIMRR 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	156/561 (28%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	145/523 (28%)
ACOS5	NP_176482.1	PLN02330	1..542	CDD:215189	158/565 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920