DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9993 and AT4G19010

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_193636.1	Gene:	AT4G19010 / 827639	AraportID:	AT4G19010	Length:	566	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	139/551 - (25%)
Similarity:	236/551 - (42%)	Gaps:	103/551 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GEVALIILRLYSDKVMQVYDPTGEELTG-------SQLLEQSRRLAHAFQRLKLQRGDVVGISAK 86
            |:.|||                 :.|||       .|::.|| ..|..:..|.:::||||.:...
plant    60 GDTALI-----------------DSLTGFSISHTELQIMVQS-MAAGIYHVLGVRQGDVVSLVLP 106

  Fly    87 NTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFEITKP------KVIFCDLDNYQTLSAVKSS 145
            |:.|...:.::.:..|..:..::|      ::.:.||.|.      .:.|...:|.:.||::..|
plant   107 NSVYFPMIFLSLISLGAIVTTMNP------SSSLGEIKKQVSECSVGLAFTSTENVEKLSSLGVS 165

  Fly   146 LKFKTEIILLTGTLPGVR----NIQDLLADGCTGYDEKTLFACPHLCGDDTAFIITSSGVTGLPK 206
            :...:|    :.....:|    ....::.:. .|:..|     |.:..||.|.|:.|||.||..|
plant   166 VISVSE----SYDFDSIRIENPKFYSIMKES-FGFVPK-----PLIKQDDVAAIMYSSGTTGASK 220

  Fly   207 GVTRSHRSLLNSAKIPQLFT--------SDTVLFCFSPLYWISCIFTLLASLVNGCRRIITNRPF 263
            ||..:||:|:.|.::...|.        |..|.....||..|..:...:..|::....|:..:.|
plant   221 GVLLTHRNLIASMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVMGLLSLGSTIVVMKRF 285

  Fly   264 SVAYFADLVERHQVSFVLTVPHHMALLAKSPERQELAAKMQCVQSF-----VCSGSKVPMGIWRQ 323
            ..:...:::||.:::....||..:..|.|.       ||..|.:.|     |.||: .|:.  |:
plant   286 DASDVVNVIERFKITHFPVVPPMLMALTKK-------AKGVCGEVFKSLKQVSSGA-APLS--RK 340

  Fly   324 LYE-----------LLGANRFAVLYGLTE-----TGGISKNVGGPLGSEGRLLRNVQVRVVD-PH 371
            ..|           :.|       ||:||     |.|.:........|.|.|..|:|.:||| ..
plant   341 FIEDFLQTLPHVDLIQG-------YGMTESTAVGTRGFNSEKLSRYSSVGLLAPNMQAKVVDWSS 398

  Fly   372 GQSLGPNQTGQILVRLNLRWGGYYHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVF 436
            |..|.|...|::.::......||.:||:.||:::..| .||.|||..|||::|.|....|..::.
plant   399 GSFLPPGNRGELWIQGPGVMKGYLNNPKATQMSIVED-SWLRTGDIAYFDEDGYLFIVDRIKEII 462

  Fly   437 KYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAVVRNEDELGAQLTEADVKGVVAQ 501
            ||..|.|.|..:|.|::..|.:.:.||...|:|....:....|||.::   ..|:|.||...||.
plant   463 KYKGFQIAPADLEAVLVSHPLIIDAAVTAAPNEECGEIPVAFVVRRQE---TTLSEEDVISYVAS 524

  Fly   502 HLSDAFHIRGGVFFVDNLPKTQNSKVQRRKI 532
            .::....:| .|..|:::||:...|:.|:::
plant   525 QVAPYRKVR-KVVMVNSIPKSPTGKILRKEL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	139/549 (25%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	134/529 (25%)
AT4G19010	NP_193636.1	PLN02574	9..566	CDD:215312	139/551 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920