DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9993 and 4CL2

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	147/543 - (27%)
Similarity:	260/543 - (47%)	Gaps:	84/543 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYLTEVVIAALLNGT 103
            ::.|...:..||||..|.:.:...||:||.....|.:::.|||.|...|:..:....:||...|.
plant    49 FAAKPCLINGPTGEVYTYADVHVTSRKLAAGLHNLGVKQHDVVMILLPNSPEVVLTFLAASFIGA 113

  Fly   104 PINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSLKFKTEIILLTGTLPGVRNIQ-- 166
            .....:|.|   |.|   ||:|              .|..|:.|.   |:..:..:..::|:|
plant   114 ITTSANPFF---TPA---EISK--------------QAKASAAKL---IVTQSRYVDKIKNLQND 155

  Fly   167 ---------DLLADGCTGYDEKTLFACPH-------LCGDDTAFIITSSGVTGLPKGVTRSHRSL 215
                     |.:.:.|..:.|.|....|.       :..:|...:..|||.|||||||..:|:.|
plant   156 GVLIVTTDSDAIPENCLRFSELTQSEEPRVDSIPEKISPEDVVALPFSSGTTGLPKGVMLTHKGL 220

  Fly   216 LNS------AKIPQL-FTSDTVLFCFSPLYWISCIFT-LLASLVNGCRRIITNRPFSVAYFADLV 272
            :.|      .:.|.| |..|.|:.|..|::.|..:.: :|.||..|...:|..: |.:....:.:
plant   221 VTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIMLCSLRVGATILIMPK-FEITLLLEQI 284

  Fly   273 ERHQVSFVLTVPHHMALLAKSPERQEL-AAKMQCVQSFVCSGSKVPMGIWRQLYELLGAN----R 332
            :|.:|:..:.||..:..:|||||.::. .:.::.|:|     ...|:|  ::|.:.:.|.    :
plant   285 QRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKS-----GAAPLG--KELEDAISAKFPNAK 342

  Fly   333 FAVLYGLTETG-------GISKNVGGPL----GSEGRLLRNVQVRVVDPH-GQSLGPNQTGQILV 385
            ....||:||.|       |.:|.   |.    |:.|.::||.:::::||. |.||..|:.|:|.:
plant   343 LGQGYGMTEAGPVLAMSLGFAKE---PFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKPGEICI 404

  Fly   386 RLNLRWGGYYHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIED 450
            |.|....||.::|..|..|:..|| ||.|||.|:.||:..|....|..::.||..|.:.|.::|.
plant   405 RGNQIMKGYLNDPLATASTIDKDG-WLHTGDVGFIDDDDELFIVDRLKELIKYKGFQVAPAELES 468

  Fly   451 VILHLPGVHEVAVFGIPDEVSTNLTACAVVRNEDELGAQLTEADVKGVVAQHLSDAFHIR-GGVF 514
            :::..|.:::|||..:.:|.:..:....|||::|   :.::|.::|..|::.:  .|:.| ..||
plant   469 LLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKD---SNISEDEIKQFVSKQV--VFYKRINKVF 528

  Fly   515 FVDNLPKTQNSKVQRRKIWSQLS 537
            |.|::||..:.|:.|:.:.::|:
plant   529 FTDSIPKAPSGKILRKDLRARLA 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	146/536 (27%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	144/526 (27%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	147/543 (27%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	146/536 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920