Protein Alignment CG9993 and ACSF2

DIOPT Version :9

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 128/534 - (23%)
• Similarity: 228/534 - (42%)
• Gaps: 64/534 - (11%)

  Fly    54 LTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTA 118
            ||.:||.|:..:.|.....:.|.:||.:|:...|:.....:.:|....|..:..::|.:.|....
Human   125 LTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELE 189

  Fly   119 YMFE------ITKPKVI-----------FC-DLDNYQTLSAVKSS-LKFKTEIILLTGTLPGVRN 164
            |:.:      :..||..           .| :::|.|. .|:||. |...|.:|.:...|||...
Human   190 YVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQP-GALKSQRLPDLTTVISVDAPLPGTLL 253

  Fly   165 IQDLLADGCT-------GYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGVTRSHRSLLNSA--- 219
            :.:::|.|.|       .|:::.| :|     .|...|..:||.||.|||.|.||.:::|::
Human   254 LDEVVAAGSTRQHLDQLQYNQQFL-SC-----HDPINIQFTSGTTGSPKGATLSHYNIVNNSNIL 312

  Fly   220 ----KIPQLFTSDTVLFCFSPLYWISCIFTL---LASLVNGCRRIITNRPFSVAYFADLVERHQV 277
                |:.:.......:...:|||  .|:.::   :..|:.|...|:.:..|:.....:.:.|.:.
Human   313 GERLKLHEKTPEQLRMILPNPLY--HCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERG 375

  Fly   278 SFVLTVPHHMALLAKSPERQELAAKMQCVQSFVCSGSKVPMGIWRQLYELLGANRFAVLYGLTET 342
            :|:...|.....:...|:.........|  ..|.:||..|..:.|.:...:......|.||.||.
Human   376 TFLYGTPTMFVDILNQPDFSSYDISTMC--GGVIAGSPAPPELIRAIINKINMKDLVVAYGTTEN 438

  Fly   343 GGIS------KNVGGPLGSEGRLLRNVQVRVVDPHGQSLGP-NQTGQILVRLNLRWGGYYHNPQE 400
            ..::      ..|.....|.||::.:.:.|:::....:|.. |..|::.:|......||:..||:
Human   439 SPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQK 503

  Fly   401 TQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFG 465
            |:..|..| ||..|||....:::|......|..|:.......|||.::||.....|.|.||.|.|
Human   504 TEEAVDQD-KWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVG 567

  Fly   466 IPDE-VSTNLTACAVVRNEDELGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQR 529
            :.|: :...:.||..:::.:|...:..:|..||.::.     |.|...:.||.|.|.|.:.|:|:
Human   568 VKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISH-----FKIPKYIVFVTNYPLTISGKIQK 627

  Fly   530 RKIWSQLSEATTHL 543
            .|:..|:..   ||
Human   628 FKLREQMER---HL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	124/521 (24%)
		AFD_class_I	45..528	CDD:302604	123/517 (24%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	128/534 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810