Protein Alignment CG9993 and ACSS3

DIOPT Version :10

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_078836.1
• Gene: ACSS3 / 79611
• HGNCID: 24723
• Length: 686
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 134/558 - (24%)
• Similarity: 217/558 - (38%)
• Gaps: 101/558 - (18%)

  Fly    41 DKVMQVYDP----TGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYLTEVVIAALLN 101
            ||:..:||.    |....|..::|||..:||....:..:::||.|.|...........::|....
Human   127 DKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARI 191

  Fly   102 GTPINPLHPDFDAETTAYMFEITKPKVIFCDL------DNYQTLSAVKSSLKF---KTEIILLTG 157
            |...:.:...|.::..:...:..||||:....      ...:.:..|:.:||.   |.:.||:..
Human   192 GAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYN 256

  Fly   158 TLPGVRNIQDLLADG-CTGYDEKTLFACPHLC----GDDTAFIITSSGVTGLPKGVTRS------ 211
            . |.:..:.  ||.| ...:||:...|..|.|    .:...:|:.:||.|||||||.|.
Human   257 R-PNMEAVP--LAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAV 318

  Fly   212 --HRSLLNSAKIPQLFTSDTVLFCFSPLYW-ISCIFTLLASLVNGCRRII-----TNRPFSVAYF 268
              |.|:   :.|..|...: |.:..|.|.| :...:.....|::|...::     ...|.:.|||
Human   319 MLHWSM---SSIYGLQPGE-VWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYF 379

  Fly   269 ADLVERHQVSFVLTVPHHMALLAKSPERQELAAKMQCV--QSFVCSGSKVPMGI--WRQLYELLG 329
            ..|.| |.|:.:.|.|..:..:.:......|..:....  ::...:|.:..:..  |.:     .
Human   380 RVLAE-HGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSK-----N 438

  Fly   330 ANRFAVL--YGLTETG--------GISKNVGGPLGSEGRLLRNVQVRVVDPHGQSLGPNQTGQIL 384
            ..|..||  :..||||        |:..:...|.|..|:.:....|.::|.:.|.|.....|.|:
Human   439 VFRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLGNIV 503

  Fly   385 VRLNL---------------------RWGGYYHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHF 428
            |:|.|                     ::.|||.                 |.|.||.|:||.|:.
Human   504 VKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYD-----------------TMDAGYMDEEGYLYV 551

  Fly   429 QSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTN--LTACAVVRNEDELGAQLT 491
            .||..||.......|....||:.||....|.:.||.|..|.:..:  |..|.:.::.:....|:.
Human   552 MSRVDDVINVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDINATEEQVL 616

  Fly   492 EADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQR 529
            |..||. |.|::......|..| ||..||||::.|:.|
Human   617 EEIVKH-VRQNIGPVAAFRNAV-FVKQLPKTRSGKIPR 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	Firefly_Luc_like	44..528	CDD:341237	131/552 (24%)
ACSS3	NP_078836.1	PrpE	62..679	CDD:341271	134/558 (24%)