Protein Alignment CG9993 and ACSM3

DIOPT Version :9

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_024306135.1
• Gene: ACSM3 / 6296
• HGNCID: 10522
• Length: 633
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 140/625 - (22%)
• Similarity: 223/625 - (35%)
• Gaps: 165/625 - (26%)

  Fly    25 DMTLG-----EVALIILRLYSDKVMQVYDPT----------GEELTGS--QLLEQSRRLAHAF-Q 71
            |..||     ..|..:|..::||......|:          |||:..|  :|...||:.|:.. :
Human    49 DFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113

  Fly    72 RLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDNY 136
            ...|||||.|.:............:|.|..||.:.|.......:...|..:.:|...|..:....
Human   114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLA 178

  Fly   137 QTLSAVKSSLK-FKTEIILLTGTLPGVRNIQDLLADGCTGYDEKTLFAC---------------- 184
            ..:.||.|..: ..:::|:...:..|..|:::|:          .:|.|
Human   179 PAVDAVASKCENLHSKLIVSENSREGWGNLKELM----------KVFLCHPGWSTVARSWLTATS 233

  Fly   185 ---------------------PHLC----GDDTAFIITSSGVTGLPKGVTRSHRSLLNSAKIPQL 224
                                 .|.|    .::...|..:||.:|.||....:|.|......:...
Human   234 TSLVQAILSLLSSWDYRHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGR 298

  Fly   225 F------------TSDT------VLFCFSPLYWI--SCIFTLLASLVNGCRRIITNRPFSVAYFA 269
            |            ||||      ....|||  ||  :|:||         ..:....|.|:   .
Human   299 FWLDLTPSDVMWNTSDTGWAKSAWSSVFSP--WIQGACVFT---------HHLPRFEPTSI---L 349

  Fly   270 DLVERHQVSFVLTVPHHMALLAKSPERQELAAKMQCVQSFVCSGSKVPMGI---WR-----QLYE 326
            ..:.::.::...:.|....:|.   :....:.|.:.::..|.:|..:...:   ||     .:||
Human   350 QTLSKYPITVFCSAPTVYRMLV---QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYE 411

  Fly   327 LLGANRFAVLYGLTETGGISKNVGG----PLGSEGRLLRNVQVRVVDPHGQSLGPNQTGQILVRL 387
              |       ||.|||..|..|..|    | ||.|:......|::||.:|..|.|.|.|.|.:::
Human   412 --G-------YGQTETVLICGNFKGMKIKP-GSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQV 466

  Fly   388 --NLRWGGYYH---NPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQ 447
              |..:|.:.|   ||.:|..|:.  |.:.:|||.||.|.:|...|.:|..||...:.:.|.|.:
Human   467 LPNRPFGLFTHYVDNPSKTASTLR--GNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFE 529

  Fly   448 IEDVILHLPGVHEVAVFGIPDEVSTNLTACAVVRNED-------ELGAQLTEADVKGVVAQH--- 502
            :|:.:...|.|.|.||...||.:...:....||.|.|       :|..::.| .||...|.:
Human   530 VENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE-HVKKTTAPYKYP 593

  Fly   503 ------------------LSDAFHIRGGVFFVDNLPKTQN 524
                              .|..|:|...:||....|...|
Human   594 RKVGILIITNICSVLWTISSVYFYILMNIFFTHAAPHVPN 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	140/625 (22%)
		AFD_class_I	45..528	CDD:302604	133/600 (22%)
ACSM3	XP_024306135.1	AFD_class_I	54..596	CDD:327384	130/581 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920