DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9993 and dip2bb

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	XP_009300851.1	Gene:	dip2bb / 568954	ZFINID:	ZDB-GENE-100729-4	Length:	1615	Species:	Danio rerio

Alignment Length:	667	Identity:	137/667 - (20%)
Similarity:	227/667 - (34%)	Gaps:	201/667 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PKDKEYYGPDMTLGEVALIILRLYSDKVMQVYDPTGEELTGSQLLEQS---RRLA------HAFQ 71
            |:.|:..|    :|..::::..|.:.|  ::....|.:|   .|:|..   |:|.      |.|.
Zfish   976 PRQKQPVG----VGPASIMVGNLVAGK--RIAQAAGRDL---GLIEDQDLVRKLCMWPTMMHQFL 1031

  Fly    72 RLKLQ-RGDV-------VGISAKNTTYLT----------EVVIAALLNGTPIN------------ 106
            ...|| |...       |.::||.....|          |.:.|||:..:.||
Zfish  1032 TEALQWRAQTDPDHTLYVLLNAKGVAVCTATCVQLHKRAEKIAAALMERSGINIGENVVLLYPPG 1096

  Fly   107 ---------------------PLHP---DFDAETTAYMFEITKPKVIFCDLDNYQTLSAV----- 142
                                 |.||   .....|...:.:::|...|.    ..|.|:.:
Zfish  1097 IDLIAAFYGCLYAGCIPVTVRPPHPQNLSATLPTVRMIIDVSKAACIL----TTQVLTKILRSKE 1157

  Fly   143 -KSSLKFKT-EIILLTGTLPGVRNIQDLLADGCTGYDEKTLFACPHLCGDDTAFIITSSGVTGLP 205
             .:::..|| .||:.|..||..|              ..|::..|:  .:..|::..|...||:.
Zfish  1158 AAATVNIKTWPIIIDTDDLPRKR--------------PPTIYKPPN--AEMIAYLDFSVSTTGML 1206

  Fly   206 KGVTRSH---RSLLNSAKIP-QLFTSDTVLFCFSPLYWISCIFTLLASLVNGCRRII---TNRPF 263
            .||..||   .:|..|.|:. :|::|..:..|..|...:..:...|||:.:|.:.|:   .....
Zfish  1207 TGVKISHAAVSALCRSIKLQCELYSSRQIAICLDPYCGLGFVLWCLASVYSGHQSILIPPMELET 1271

  Fly   264 SVAYFADLVERHQVSFVLTVPHHMALLAKSPERQ-EL----AAKMQCVQSFVCSGSKVP----MG 319
            |:..:...:.::::.........|.|..|....| ||    ...:.||:|.|....:.|    ..
Zfish  1272 SLTLWLGTLSQYRIRDTFCSYSVMELCTKGLGGQTELLKARGVNLSCVRSCVVIAEERPRLALTH 1336

  Fly   320 IWRQLYELLGANRFAV-------------LYGLTETG---------------------GISKNVG 350
            .:.:|::.:|.:..||             |.|.|...                     |..:::
Zfish  1337 SFSKLFKDIGLSMRAVSTAFGSRVNLAICLQGTTGPDPSTVYVDMKSLRHDRVRLVERGAPQSL- 1400

  Fly   351 GPLGSEGRLLRNVQVRVVDPHGQS-LGPNQTGQILVRLNLRWGGYY-----HNPQ----ETQVTV 405
             ||...|.:|..|:|.:|:|..:. ||.:..|:|.|.......|||     .|.|    .|:::.
Zfish  1401 -PLMESGTILPGVRVVIVNPETRGPLGDSHLGEIWVNSPHNATGYYTIYGEENLQADHFNTKLSF 1464

  Fly   406 -TPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPG------------ 457
             .|...|..||..|:..       ::..||.....|..::.....|..|.|.|
Zfish  1465 GDPQTLWARTGYLGFVK-------RTELTDASGDRHDALFVVGYLDETLELRGLRYHPIDIETSV 1522

  Fly   458 ------VHEVAVFGIPDEVSTNLTACAVVRNEDEL-GAQLTEADVKGVVAQHLSDAFH-IRGGVF 514
                  :.|.|||     ..|||.....     || |::....|:..:|...:.:..| |.|.|.
Zfish  1523 SRAHRSIGESAVF-----TWTNLLVVVA-----ELCGSEQDALDLVPLVTNVVLEEHHLIVGVVV 1577

  Fly   515 FVDN--LPKTQNSKVQR 529
            .||.  :|.....:.||
Zfish  1578 IVDPGVIPINSRGEKQR 1594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	135/662 (20%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	129/635 (20%)
dip2bb	XP_009300851.1	DMAP_binding	9..137	CDD:283995
		Dip2	391..955	CDD:213273
		AFD_class_I	1052..1604	CDD:327384	119/582 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900