Protein Alignment CG9993 and SLC27A1

DIOPT Version :10

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 133/561 - (23%)
• Similarity: 226/561 - (40%)
• Gaps: 77/561 - (13%)

  Fly    27 TLGEVALIILRLYSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYL 91
            |:..:...:::...:::..|...|||..|.:||...|..:|:.|::|....||||.|..:.....
Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEF 141

  Fly    92 TEVVIAALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAV-----KSSLKFKTE 151
            ..:.:.....|.....|:.:...|..|:....:..|.:....:....::.|     ||.:||.:.
Human   142 VGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSG 206

  Fly   152 IILLTGTLPGVRNIQDLLADGCTGYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGV----TRSH 212
            .:...|.||....:..||.:..|.    .|...|....||..|.|.:||.|||||..    :|.:
Human   207 DLGPEGILPDTHLLDPLLKEASTA----PLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYY 267

  Fly   213 RSLLNSAKIPQLFTSDTVLFCFSPLYW-ISCIFTLLASLVNGCRRIITNRPFSVA-YFADLVE-- 273
            |.........::..:|.:..|. |||. ...|..:...|:.|. .::..:.||.: ::.|.::
Human   268 RMAAFGHHAYRMQAADVLYDCL-PLYHSAGNIIGVGQCLIYGL-TVVLRKKFSASRFWDDCIKYN 330

  Fly   274 ------RHQVSFVLTVPHHMAL---LAKSPERQELAAKMQCVQSFVCSGSKVPMGIWRQLYELLG 329
                  ||.....|.|.:...:   |.|.|.|:  |.:...|:..|  |:.:...||.:..|..|
Human   331 CTINGVRHCRLLCLVVQYIGEICRYLLKQPVRE--AERRHRVRLAV--GNGLRPAIWEEFTERFG 391

  Fly   330 ANRFAVLYGLTETGGISKNVGGPLGSEG---RLLRNV-QVRVV-----------DPHGQSLGPNQ 379
            ..:....||.||......|:.|.:||.|   |:|.:| .:|:|           |..|..: |.|
Human   392 VRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCI-PCQ 455

  Fly   380 TGQ--ILV-RLN-----LRWGGYYHNPQETQ-----VTVTPDGKWLLTGDHGYFDDEGCLHFQSR 431
            .|:  :|| ::|     .|:.||......::     |....|..: |:||....|:.|.::|:.|
Human   456 AGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAY-LSGDVLVMDELGYMYFRDR 519

  Fly   432 DTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIP-DEVSTNLTACAVVRNEDELGAQLTEADV 495
            ..|.|::....:...::|.|:..|.|..:|||:|:. ..|.......||......|.......::
Human   520 SGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLLDPNAIYQEL 584

  Fly   496 KGVVAQHLSDAFHIR-------GGVFFVDNLPKTQNSKVQR 529
            :.|:|.:....| :|       .|.|      |.|.:::||
Human   585 QKVLAPYARPIF-LRLLPQVDTTGTF------KIQKTRLQR 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	Firefly_Luc_like	44..528	CDD:341237	130/541 (24%)
SLC27A1	XP_011526302.1	Adenylate forming domain, Class I superfamily	101..623	CDD:473059	130/537 (24%)