DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9993 and Acsm5

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001014184.3	Gene:	Acsm5 / 361637	RGDID:	1309578	Length:	578	Species:	Rattus norvegicus

Alignment Length:	527	Identity:	125/527 - (23%)
Similarity:	213/527 - (40%)	Gaps:	76/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 TGEEL--TGSQLLEQSRRLAHAFQ-RLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPD 111
            :|.|:  |..:|.:|||:.|:..: ...|:.||.:.:...........::|.:..|..:.|....
  Rat    83 SGTEVKWTFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQ 147

  Fly   112 FDAETTAYMFEITKPKVIFCD---LDNYQTLSAVKSSLKFKTEIILLTGTLPGVRNIQDLLADGC 173
            ...:...|..:..:.|.|...   ..:...:||...||  ::.:::...:.||..|.::||.
  Rat   148 LTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSL--QSRLLVSDTSRPGWINFRELLR--- 207

  Fly   174 TGYDEKTLFACP-HLC-----GDDTAFIITSSGVTGLPKGVTRSHRS----LLNSAKIPQLFTSD 228
                    .|.| |.|     ||..|...| ||.||.||.|..|..|    .:.|.:.....|..
  Rat   208 --------VASPEHNCLRTRSGDSMAIYFT-SGTTGTPKMVEHSQCSYGLGFVASGRRLMALTES 263

  Fly   229 TVLFCFSPLYWISCIFTLLASLVNGCRRIITNRP-FSVAYFADLVERHQVSFVLTVPHHMALLAK 292
            .:.:..:...|:...:||.::..||....:...| .......:.:.|..::.:..||....||.
  Rat   264 DIFWNTTDTGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLV- 327

  Fly   293 SPERQELAA-KMQCVQSFVCSGSKVPMGI---WR-----QLYELLGANRFAVLYGLTETGGISKN 348
               :::|.. |.||::..:..|..:...:   |:     :::|  |       ||.:||..|..|
  Rat   328 ---QEDLTRYKFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHE--G-------YGQSETVLICGN 380

  Fly   349 VGGPL---GSEGRLLRNVQVRVVDPHGQSLGPNQTGQILVRLN-----LRWGGYYHNPQETQVTV 405
            ..|..   ||.|:......|::||..|..|.|.:.|.|.:|:.     ..:..|..||::|  ..
  Rat   381 FRGSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKT--AA 443

  Fly   406 TPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEV 470
            :..|.:.:|||..:.|::|...|..|:.||...:.:.|.|.::|..:...|.|.|.||...||.:
  Rat   444 SEQGDFYITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPI 508

  Fly   471 STNLTACAVV-------RNEDELGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQ 528
            ...:....:|       .:.:.|..:|.| .||.|.|     .:.....|.|:..||||.:.|:.
  Rat   509 RGEVVKAFIVLSPAYVSHDPEALTRELQE-HVKTVTA-----PYKYPRKVAFISELPKTVSGKIL 567

  Fly   529 RRKIWSQ 535
            |.|:.:|
  Rat   568 RSKLRNQ 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	123/522 (24%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	122/518 (24%)
Acsm5	NP_001014184.3	AFD_class_I	48..576	CDD:418409	125/527 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010