DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9993 and Acsm4

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_859046.1	Gene:	Acsm4 / 353317	RGDID:	727928	Length:	580	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	127/518 - (24%)
Similarity:	215/518 - (41%)	Gaps:	59/518 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GEELTGS--QLLEQSRRLAHAFQR-LKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDF 112
            |:|:..|  :|...||:.|:...: ..|||||.|.:..........:.:|.:..|....|.....
  Rat    84 GDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQL 148

  Fly   113 DAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSL-KFKTEIILLTGTLPGVRNIQDLLADGCTGY 176
            ..:...|..:.:|.|.|....:....:.::.|.. ..||::::......|..:.|:||......:
  Rat   149 TRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEH 213

  Fly   177 DEKTLFACPHLCGDDTAFIITSSGVTGLPKGVTRSHRSL-LNSAKIPQLF---TSDTVLFCFSPL 237
            :      |......:...|..:||.||.||....|..|| :..|...:.:   ||..:::..|..
  Rat   214 N------CVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDT 272

  Fly   238 YWI-SCIFTLLASLVNG-CRRIITNRPFSVAYFADLVERHQVSFVLTVPH-HMALLAKSPERQEL 299
            .|| :.|.::.::.:.| |..:.....|:...|.|.:..:.::.:.:.|. :..|:.:..:|.:.
  Rat   273 GWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKRYQF 337

  Fly   300 AAKMQC------VQSFVCSGSKVPMGIWRQLYELLGANRFAVLYGLTETGGISKNVGG----PLG 354
            .....|      :...|....|...|:  :|||  |       ||.||.|.|..|..|    | |
  Rat   338 KRLRHCLTGGEPLNPEVLEQWKAQTGL--ELYE--G-------YGQTEVGIICANRKGEEIKP-G 390

  Fly   355 SEGRLLRNVQVRVVDPHGQSLGPNQTGQILVRLN-----LRWGGYYHNPQETQVTVTPDGKWLLT 414
            |.|:.:....|:::|.||..|...:.|:|.:||.     ..:..|..||::|..|:..:  :.:|
  Rat   391 SMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRN--FYIT 453

  Fly   415 GDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAV 479
            ||.|..||:|.|.|..|..||...:.:.|.|.::|..::..|.|.|.||...||.:...:....:
  Rat   454 GDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFI 518

  Fly   480 V-------RNEDELGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRRKIWSQ 535
            |       .|.::|.|:|.: .||...|     .:.....|.||..||||...|::|..:..|
  Rat   519 VLAAPFKSSNREKLTAELQD-HVKNSTA-----PYKYPRKVEFVQELPKTITGKIKRNVLRDQ 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	126/513 (25%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	125/509 (25%)
Acsm4	NP_859046.1	MACS_euk	48..577	CDD:341251	127/518 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920