Protein Alignment CG9993 and ACSM2B

DIOPT Version :9

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001098539.1
• Gene: ACSM2B / 348158
• HGNCID: 30931
• Length: 577
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 135/525 - (25%)
• Similarity: 221/525 - (42%)
• Gaps: 62/525 - (11%)

  Fly    51 GEELTGS--QLLEQSRRLAHAFQ-RLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDF 112
            |:||..:  :|.|.|::.|:... ...|||||.|.:..........|::..:..|....|.....
Human    76 GKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140

  Fly   113 DAETTAYMFEITKPKVIFCDLDNYQTLSAVKS---SLKFKTEIILLTGTLPGVRNIQDLLADGCT 174
            .:....|..:::|.|.|....:..|.:..|.|   ||:.|  :::...:..|..|.:.||.:..|
Human   141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK--LLVSEKSCDGWLNFKKLLNEAST 203

  Fly   175 GYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGVTRSHRSLLNSAKIPQLFT---SDTVLFCFSP 236
            .:.      |......:.:.|..:||.:||||....|:.||...||:...:|   :..:::..|.
Human   204 THH------CVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISD 262

  Fly   237 LYWI-SCIFTLLASLVNGCRRIITNRP-FSVAYFADLVERHQVSFVLTVP--HHMALLAKSPERQ 297
            ..|| :.:.:||.|...|....:...| |........:..:.:..::..|  :.|.|      :|
Human   263 TGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLL------QQ 321

  Fly   298 ELAA-KMQCVQSFVCSG-SKVPMGI--WRQLYELLGANRFAVLYGLTETG---GISKNVGGPLGS 355
            :|:: |...:|:.:..| |.:|..:  ||....|    .....||.||||   .:||.:....|.
Human   322 DLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL----DIREFYGQTETGLTCMVSKTMKIKPGY 382

  Fly   356 EGRLLRNVQVRVVDPHGQSLGPNQTGQILVRLN-LR----WGGYYHNPQETQVTVTPDGKWLLTG 415
            .|.......|:|:|..|..|.|...|.|.:|:. :|    :.||..||.:|...:..| .||| |
Human   383 MGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGD-FWLL-G 445

  Fly   416 DHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAVV 480
            |.|..|::|...|..|..|:...:.:.|.|.::|:.::..|.|.|.||...||.|...:....|:
Human   446 DRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510

  Fly   481 -------RNEDELGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRRKI----WS 534
                   .:.::|..:| :..||.|.|     .:.....:.||.|||||...|:||.|:    |.
Human   511 LASQFLSHDPEQLTKEL-QQHVKSVTA-----PYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 569

  Fly   535 QLSEA 539
            ...:|
Human   570 MSGKA 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	132/512 (26%)
		AFD_class_I	45..528	CDD:302604	130/508 (26%)
ACSM2B	NP_001098539.1	AFD_class_I	40..568	CDD:388389	133/517 (26%)
		Coenzyme A binding. /evidence=ECO:0000250	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000250	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920