Protein Alignment CG9993 and ACSL6

DIOPT Version :10

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 674
• Identity: 146/674 - (21%)
• Similarity: 226/674 - (33%)
• Gaps: 224/674 - (33%)

  Fly     2 ASTKYDSFEKIWS----GP-----KDKEYYGPDMTLGEVALIILRLYSDKVMQVYDPTGEELTGS 57
            |.|.|..|.:..|    ||     |.|:.| ..::..|||        |:.         |..||
Human   114 ARTMYQVFRRGLSISGNGPCLGFRKPKQPY-QWLSYQEVA--------DRA---------EFLGS 160

  Fly    58 QLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFE 122
            .||:.:         .|......:|:.|:|......|.:|.......:.||:.........|:..
Human   161 GLLQHN---------CKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIIN 216

  Fly   123 ITKPKVIFCDLDNYQTLSAVKSSLKFKTEIILLTGT----LPGVRNIQDLLAD-----------G 172
            ......:..|              |.:..::||...    .||::.|  :|.|           .
Human   217 TADISTVIVD--------------KPQKAVLLLEHVERKETPGLKLI--ILMDPFEEALKERGQK 265

  Fly   173 CTGYDEKTLFACPHLCG------------DDTAFIITSSGVTGLPKGVTRSHRSLL--------- 216
            | |...|::.|... ||            ||.:.:..:||.||.|||...:|.:::
Human   266 C-GVVIKSMQAVED-CGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKV 328

  Fly   217 -NSAKIPQLFTSDTVLFCFSPLYWISCIFTLLASLVNGCRRIITNRPFSVAYF-------ADLVE 273
             .|...|   |...|...:.||   :.:|..:...|..|      ....|.:|       :|.::
Human   329 TESQWAP---TCADVHISYLPL---AHMFERMVQSVVYC------HGGRVGFFQGDIRLLSDDMK 381

  Fly   274 RHQVSFVLTVPHHMALL-------AKSPERQ---ELAAKMQCVQSFVCSGSKVPMGIWRQLY--- 325
            ....:....||..:..:       |.:|.::   |.|||.:  |:.|.||......||.:|:
Human   382 ALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRK--QAEVRSGIIRNDSIWDELFFNK 444

  Fly   326 ---ELLGANRFAVL------------------------YGLTE-TGG---------ISKNVGGPL 353
               .|.|..|..|.                        ||.|| |.|         .|.:||.||
Human   445 IQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPL 509

  Fly   354 GSEGRLLRNVQVRVVDPH--------GQSLGPNQTGQILVRLNLRWGGYYHNPQETQVTVTPDGK 410
            ...       .:::||..        |:       |:|.||....:.||..:|..|:..:..||
Human   510 PCN-------HIKLVDVEELNYWACKGE-------GEICVRGPNVFKGYLKDPDRTKEALDSDG- 559

  Fly   411 WLLTGDHGYFDDEGCLHFQSRDTDVFK-----YNHFPIYPKQIEDVILHLPGVHEVAVFG----- 465
            ||.|||.|.:...|.|....|...:||     |    :.|::||::.:....|.::.|.|
Human   560 WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEY----VAPEKIENIYIRSQPVAQIYVHGDSLKA 620

  Fly   466 ------IPD-EVSTNLTACAVVRNEDELGAQL-TEADVKGVVAQHL--------------SDAFH 508
                  :|| ||   :.:.|..|..:...|.| |..|:|..:.:.:              ..|.|
Human   621 FLVGIVVPDPEV---MPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIH 682

  Fly   509 IRGGVFFVDNLPKTQNSKVQRRKI 532
            |...:|.|.|...|...|.:|.::
Human   683 IHSDMFSVQNGLLTPTLKAKRPEL 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	Firefly_Luc_like	44..528	CDD:341237	131/617 (21%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	137/647 (21%)