Protein Alignment CG9993 and DIP2A

DIOPT Version :9

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_011527794.1
• Gene: DIP2A / 23181
• HGNCID: 17217
• Length: 1607
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 125/575 - (21%)
• Similarity: 197/575 - (34%)
• Gaps: 148/575 - (25%)

  Fly    58 QLLEQSRRLAHA-FQRLKLQRGDVVGISAKNTTYLTEVVIAALLNG--------TPINPLHPD-- 111
            ||.:::.|:|.| .::.:|..||.|.:     .|...|.:.|...|        ..:.|.||.
Human  1057 QLHKRAERVAAALMEKGRLSVGDHVAL-----VYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNL 1116

  Fly   112 -FDAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSLKFKTEIILL-TGTLPGVRNIQDL----LA 170
             ....|...:.|::|...:.       |..||...|:.|.....: ..|.|.:.:..|:    :|
Human  1117 GTTLPTVKMIVEVSKSACVL-------TTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIA 1174

  Fly   171 DGCTGYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGVTRSH---RSLLNSAKIP-QLFTSDTVL 231
                     ::|..|  ..|..|::..|...||:..||..||   .:|..|.|:. :|:.|..:.
Human  1175 ---------SVFRPP--SPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIA 1228

  Fly   232 FCFSPLYWISCIFTLLASLVNGCRRIIT---NRPFSVAYFADLVERHQVSFVLTVPHHMALLAKS 293
            .|..|...:......|.|:.:|.:.::.   ....:|:.:...|.:::..........|.:..|.
Human  1229 ICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKG 1293

  Fly   294 PERQELAAKMQ-----CVQSFVCSGSKVP----MGIWRQLYELLGANRFAVLYGLTETGGISKNV 349
            ...|....:|:     ||::.:....:.|    ...:.:|::.||....||    :.|.|...||
Human  1294 LGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAV----STTFGCRVNV 1354

  Fly   350 G----GPLGSEG-------RLLRNVQVRVVD---PHG-----------------------QSLGP 377
            .    |..|.:.       |.||:.:||:|:   ||.                       ..||.
Human  1355 AICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGD 1419

  Fly   378 NQTGQILVRLNLRWGGYYHNPQETQVTVTPDGKWLLTGDH-----GYFDDE------GCLHFQSR 431
            :..|:|.|.......|||          |..|:..|..||     .:.|.:      |.|.|..|
Human  1420 SHLGEIWVSSPHNATGYY----------TVYGEEALHADHFSARLSFGDTQTIWARTGYLGFLRR 1474

  Fly   432 D--TDVFKYNHFPIYPKQIEDVILHLPG------------------VHEVAVFGIPDEVSTNLTA 476
            .  ||.....|..:|.....|..|.|.|                  :.|.|||     ..|||..
Human  1475 TELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVF-----TWTNLLV 1534

  Fly   477 CAVVRNEDELGAQLTEADVKGVVAQHLSDAFHIRGGVFFVDN--LPKTQNSKVQR 529
            ..|..:..|..|....|.|..||   |.:.:.:.|.|..||.  :|.....:.||
Human  1535 VVVELDGLEQDALDLVALVTNVV---LEEHYLVVGVVVIVDPGVIPINSRGEKQR 1586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	125/575 (22%)
		AFD_class_I	45..528	CDD:302604	123/572 (22%)
DIP2A	XP_011527794.1	DMAP_binding	9..158	CDD:283995
		CaiC	360..959	CDD:223395
		AFD_class_I	392..956	CDD:302604
		AMP-binding	1027..1501	CDD:278902	101/480 (21%)
		AFD_class_I	1044..1596	CDD:302604	125/575 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900