Protein Alignment CG9993 and ACSL1

DIOPT Version :9

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001273637.1
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 135/635 - (21%)
• Similarity: 220/635 - (34%)
• Gaps: 202/635 - (31%)

  Fly    38 LYSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRG------DVVGISAKNTTYLTEVVI 96
            |.|.|..|.|    |.|:..|:.|.|..:..|.    :|:|      ..:||.|:|......:..
Human   109 LGSRKPDQPY----EWLSYKQVAELSECIGSAL----IQKGFKTAPDQFIGIFAQNRPEWVIIEQ 165

  Fly    97 AALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSLKFKTEIILLTGT--- 158
            ........|.||:.....|...|:....:..::|.|              |.:...:||.|.
Human   166 GCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVD--------------KPEKAKLLLEGVENK 216

  Fly   159 -LPGVRNI-------QDLLADG--CTGYDEKTLFACPHL-----------CGDDTAFIITSSGVT 202
             :||::.|       .:|:..|  | |.:..::.|...|           ..:|.|.|..:||.|
Human   217 LIPGLKIIVVMDAYGSELVERGQRC-GVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTT 280

  Fly   203 GLPKGVTRSHRSLLNSAKIPQLFTSDTV-------LFCFSPLYW-----ISCIFTLLASLVNGCR 255
            |.|||...:||::::........|.:||       |..|.||..     :.|:.     |.:|.:
Human   281 GNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM-----LCHGAK 340

  Fly   256 RIITNRPFSVAYF-------ADLVERHQVSFVLTVPHHMA-----------------LLAKSPER 296
                     :.:|       .|.::..|.:....||..:.                 ||..:.:|
Human   341 ---------IGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKR 396

  Fly   297 QE-----------------LAAKMQC-----VQSFVCSGSKVPMGIWRQLYELLGANRFAVLYGL 339
            :|                 :..|:|.     |:..|...:.|...:...|...||. :|...||.
Human   397 KEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGC-QFYEGYGQ 460

  Fly   340 TE-TGG---------ISKNVGGPLGSEGRLLRNVQVRVVDPHGQSLGPNQTGQILVRLNLRWGGY 394
            || |.|         .:.:||.|:..  .|::.|.|..::    .:.....|::.|:....:.||
Human   461 TECTAGCCLTMPGDWTAGHVGAPMPC--NLIKLVDVEEMN----YMAAEGEGEVCVKGPNVFQGY 519

  Fly   395 YHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFK-----YNHFPIYPKQIEDVILH 454
            ..:|.:|...:..|| ||.|||.|.:...|.|....|...:||     |    |.|::||::.:.
Human   520 LKDPAKTAEALDKDG-WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEY----IAPEKIENIYMR 579

  Fly   455 LPGVHEVAVFG-----------IPDEVSTNLTACA-------------VVRNEDELGAQLTE--- 492
            ...|.:|.|.|           :||..    |.|:             :.||:|...|.|.:
Human   580 SEPVAQVFVHGESLQAFLIAIVVPDVE----TLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVR 640

  Fly   493 ----------ADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRRKI 532
                      ..|||:.         :...:|.:||...|...|.:|.::
Human   641 LGKDSGLKPFEQVKGIT---------LHPELFSIDNGLLTPTMKAKRPEL 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	135/633 (21%)
		AFD_class_I	45..528	CDD:302604	131/622 (21%)
ACSL1	NP_001273637.1	LC-FACS_euk	116..694	CDD:341250	132/628 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930