Protein Alignment CG9993 and mec-18

DIOPT Version :10

• Sequence 1: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_508731.3
• Gene: mec-18 / 180701
• WormBaseID: WBGene00003179
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 135/581 - (23%)
• Similarity: 241/581 - (41%)
• Gaps: 134/581 - (23%)

  Fly     1 MASTKYDSFEKIWSGPKDKEYYGPDMTLGEVALIILRLYSDKVMQVYDPTGE--ELTGSQLLEQS 63
            :|...:::.::||             ||.:::.....:..::.||..|....  ::.|...::..
 Worm    97 VAVNGWNAVDEIW-------------TLVDLSEATHLIVENQFMQKADDVRRKAQMRGGGRIKHV 148

  Fly    64 RRLAHAF--QRLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFEIT-K 125
            |::....  :|:.:.......|..|....|.:.:..|.:|.||:   .|:..|:.|:.:.|:: :
 Worm   149 RQIEDVLTAERINVDSARKRSIDVKQKPPLVKEMSLAKINLTPV---LPEDIADLTSPVSEVSGQ 210

  Fly   126 PKVIFCDLDNYQTLSAVKSSLKFKTEIILLTGTLPGVRNIQDLLADGCTGYDEKTLFACPHLCGD 190
            .|.:..|::     |:|..|.:.:|.|..::|..|
 Worm   211 SKELNGDVE-----SSVVDSEEVQTPIQQVSGQNP------------------------------ 240

  Fly   191 DTAFIITSSGVTGLPKGVTRSHRSLLNSAKIPQLFTSDTVLFCFSPLYW-------------ISC 242
              ..|:.:||.|||.|....|||||:  ..|.|:..         |||.             |:.
 Worm   241 --LLILFTSGTTGLAKAAELSHRSLI--INIQQISL---------PLYGPVQTKERFLLPLSIAH 292

  Fly   243 IFTLLA---SLVNGCRRIITNRPFSVAYFADLVERHQVSFVLTVP---HHMALLA-----KSPER 296
            |:.:::   :|:||....:.::. |...|.:.:..:|::.:...|   |.||..|     |:|.
 Worm   293 IYGIVSAYYALINGASLYLISKQ-SNRLFMETLVNNQINVMHITPAIVHWMATDAIVDDYKTPN- 355

  Fly   297 QELAAKMQCVQSFVCSGSKVPMGIWRQLYELLGANRFAVLYGLTETGGIS----------KNVGG 351
                     ::|.:|:|:.:.......:...|....|...:|:||.|||.          ::||.
 Worm   356 ---------LRSVLCAGAPIDSNSAAAMKSRLNIKDFRQSFGMTELGGICTMSPYLDEKIESVGN 411

  Fly   352 PLGSEGRLLRNVQVRVVDPHGQSLG-PNQTGQILVRLNLRWGGYYHNPQETQVTVTPDGKWLLTG 415
            ||  .|.|.     :||:...:.|. |.|.|||:|........||.||:.|.......| ::.||
 Worm   412 PL--PGMLF-----KVVNWETKQLCLPRQPGQIIVLGPQVSPCYYKNPKATSELFDATG-FVKTG 468

  Fly   416 DHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAVV 480
            |.|::|:.|.::...|..|:.|.....|.|.::|.|:....|:.:.||.|..|.|:..:.|..||
 Worm   469 DAGFYDEVGRIYVLDRIKDIIKCKGTMICPSEVELVLRAHAGIDDCAVVGRQDHVTGEVPAAFVV 533

  Fly   481 RNEDELGAQ---LTEADVKGVVAQHLSDAFHIRGGVFFVDNLPKTQNSKVQRRKI---WSQ 535
            :|     ||   |..|:|:..|:..::....:||||||:..:|::...|:.||.:   |.:
 Worm   534 KN-----AQHPLLASAEVRQYVSGKIATFKELRGGVFFISEIPRSVCGKILRRNLRQFWDR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	Firefly_Luc_like	44..528	CDD:341237	127/526 (24%)
mec-18	NP_508731.3	Firefly_Luc_like	35..579	CDD:341237	132/569 (23%)