Protein Alignment CG17999 and caiC

DIOPT Version :10

• Sequence 1: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_414579.4
• Gene: caiC / 944886
• ECOCYCID: EG11558
• Length: 517
• Species: Escherichia coli
• Alignment Length: 573
• Identity: 125/573 - (21%)
• Similarity: 212/573 - (36%)
• Gaps: 134/573 - (23%)

  Fly    21 DFYGPEMTLGEVIMRVLQINADQVMQICDTTG---QELTGAQLAQQSARIAQAFKRLGLRRGDVV 82
            |.||.:..|                 ||:::|   ...:..:|.|:..|.|..|..||:|:||.|
E. coli    18 DVYGHKTAL-----------------ICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKV 65

  Fly    83 GISANNS-----TYLTSVIIAALLRGIPIN---------------------------PLHPEFTE 115
            .:..:|.     .:.....|.|::  :|||                           |::.:..:
E. coli    66 ALHLDNCPEFIFCWFGLAKIGAIM--VPINARLLCEESAWILQNSQACLLVTSAQFYPMYQQIQQ 128

  Fly   116 ETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAA 180
            |      |.|:.:         ||..|   .:..||.        :||...:::.|.:.:....|
E. coli   129 E------DATQLR---------HICLT---DVALPAD--------DGVSSFTQLKNQQPATLCYA 167

  Fly   181 YVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSL---------LCNCKNPNTYTRDSVLLSFSP 236
                |.|..|.||.|:.:||||..||||..:|.:|         .|..::      |.|.|:..|
E. coli   168 ----PPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRD------DDVYLTVMP 222

  Fly   237 LYWIS-GTIILLASLLNGCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMEL 300
            .:.|. .....:|:...|...::..: ||.......|.:::.|........|..|........:.
E. coli   223 AFHIDCQCTAAMAAFSAGATFVLVEK-YSARAFWGQVQKYRATVTECIPMMIRTLMVQPPSANDQ 286

  Fly   301 KAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNVGGPVGCE-------- 357
            :.:|:.:...:....:...|.|.|.     ..|.:..||::|      .:.|.:|..
E. coli   287 QHRLREVMFYLNLSEQEKDAFCERF-----GVRLLTSYGMTE------TIVGIIGDRPGDKRRWP 340

  Fly   358 --GKVMRNVELRVLDKLKMPLGINEVGIIY-----ARLRFKWAGYYRNPEATRRALSSDGMWFRT 415
              |:|....|..:.|....||...|:|.|.     .:..||  .|:.||:||.:.|.:|| |..|
E. coli   341 SIGRVGFCYEAEIRDDHNRPLPAGEIGEICIKGIPGKTIFK--EYFLNPQATAKVLEADG-WLHT 402

  Fly   416 GDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDAVSTNLTACAV 480
            ||.||.|.|.:.|...|..::.|.....:...::|..|...|.:.:..|.||.|::........|
E. coli   403 GDTGYRDEEDFFYFVDRRCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDEAIKAFV 467

  Fly   481 VRTKSPEGERLTADHIRNIVEHHLSGAYHIRGGVYFIDSLPKTPNDKLQRRKV 533
            |..   |||.|:.:......|.::: .:.:...:.....||:..:.|:.|:.:
E. coli   468 VLN---EGETLSEEEFFRFCEQNMA-KFKVPSYLEIRKDLPRNCSGKIIRKNL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	Firefly_Luc_like	45..529	CDD:341237	120/543 (22%)
caiC	NP_414579.4	caiC	1..517	CDD:181195	125/573 (22%)