Protein Alignment CG17999 and Aacs

DIOPT Version :9

• Sequence 1: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_084486.1
• Gene: Aacs / 78894
• MGIID: 1926144
• Length: 672
• Species: Mus musculus
• Alignment Length: 602
• Identity: 138/602 - (22%)
• Similarity: 231/602 - (38%)
• Gaps: 136/602 - (22%)

  Fly    22 FYGPEMTLGEVIMRVLQINADQVMQICDTTGQE----LTGAQLAQQSARIAQAFKRLGLRRGD-V 81
            |.|..:...|.::|  ....|:|.......|:|    :|..:|.||.|..|.|.:::|:::|| |
Mouse    94 FRGSRLNYAENLLR--HKENDRVALYVAREGREEIVKVTFEELRQQVALFAAAMRKMGVKKGDRV 156

  Fly    82 VGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFC-------DVENYHI 139
            ||. ..||.:....::||...|...:...|:|....|...:...:||:||.       ..|:.|:
Mouse   157 VGY-LPNSAHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHGHL 220

  Fly   140 IK---TVNGKLQNPAKIYLVNGKL-EGVLDISEMLND---EDSITAAAYVPCPKLHGD-----HT 192
            .|   .|.| |.:..::.|:...| ...:|||::.|.   :|.:.:......|:|..:     |.
Mouse   221 EKLQRVVKG-LPDLQRVVLIPYVLPREKIDISKIPNSVFLDDFLASGTGAQAPQLEFEQLPFSHP 284

  Fly   193 AFIVCSSGTTGMPKGVTRS-HRSLLCNCKN---PNTYTRDSVLLSFSPLYWISGTIILLASLLNG 253
            .||:.||||||.||.:..| ..:|:.:.|.   ....|...:||.::.:.|:... .::::|..|
Mouse   285 LFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHMLHGNMTSSDILLYYTTVGWMMWN-WMVSALATG 348

  Fly   254 CRRIITNRPYSV---EYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGS 315
            ...::.:....|   ..|..||.|..:|.|...:..:::|.:.|...:|.. .|.::..::..||
Mouse   349 ASLVLYDGSPLVPTPNVLWDLVDRIGITILGTGAKWLSVLEEKDMKPVETH-NLHTLHTILSTGS 412

  Fly   316 KVCKAVCRRMYELIGNQRFVVGYGLSEMGGL---------------------SKNVGGPVGC--- 356
            .:.......:|..| ....::|   |..||.                     ::|:|..|..
Mouse   413 PLKAQSYEYVYRCI-KSSVLLG---SISGGTDIISCFMGQNSSIPVYKGEIQARNLGMAVEAWDE 473

  Fly   357 EGKVMRNVELRVLDKLKMP-----LGINEVGIIYARLRFK-----WA--GYYR-NPEATRRALSS 408
            |||.:......::....:|     ...:|.|..|.:..|.     ||  .|.| ||
Mouse   474 EGKAVWGASGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCRINP--------- 529

  Fly   409 DGMWFRTGDIGYLD-SEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDAVS 472
                 :||.|..|. |:|     |.:.:..:|.:.:|| ..:|.|                |.|.
Mouse   530 -----KTGGIIMLGRSDG-----TLNPNGVRFGSSEIY-NIVEAF----------------DEVE 567

  Fly   473 TNLTAC-----------AVVRTKSPEGERLTAD---HIRNIVEHHLSGAYHIRGGVYFIDSLPKT 523
            .:|  |           .|:..|...|.....|   .||:.:...|| |.|:...:.....:|.|
Mouse   568 DSL--CVPQYNRDGEERVVLFLKMASGHTFQPDLVKRIRDAIRLGLS-ARHVPSLILETRGIPYT 629

  Fly   524 PNDKLQRRKVLGLVQQL 540
            .|.|    ||...|:|:
Mouse   630 LNGK----KVEVAVKQV 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	136/599 (23%)
		AFD_class_I	38..529	CDD:302604	130/573 (23%)
Aacs	NP_084486.1	ac_ac_CoA_syn	16..671	CDD:273507	138/602 (23%)
		AACS	40..663	CDD:213308	138/602 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S3159
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950