DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and Slc27a2

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_113924.2	Gene:	Slc27a2 / 65192	RGDID:	71103	Length:	620	Species:	Rattus norvegicus

Alignment Length:	556	Identity:	113/556 - (20%)
Similarity:	207/556 - (37%)	Gaps:	116/556 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 QELTGAQLAQQSARIAQAF-KRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEE 116
            :.||.||:.::|.::|:|. ..||||:||.|.:...|......:.:..|..|.|:..|:.....:
  Rat    77 ETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAK 141

  Fly   117 TVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAAY 181
            ::.:.:.....||:....|.:..::.|...|:..........:......:..:|:..|.::|.
  Rat   142 SLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGMSVFYVSRTSNTNGVDTVLDKVDGVSAD-- 204

  Fly   182 VPCPKLHGDHTAF-----IVCSSGTTGMPKGVTRSHRSLLCNCK---NPNTYTRDSVLLSFSPLY 238
             |.|:.......|     .:.:|||||:||..|.:|..|.....   .......| |:.:..|||
  Rat   205 -PIPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTSLALRSGIKAHD-VIYTTMPLY 267

  Fly   239 WISGTIILLASLLNGCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQ 303
            ..:..:|    .|:||  |:....:::        |.|    |.||.......|:::.|::...:
  Rat   268 HSAALMI----GLHGC--IVVGATFAL--------RSK----FSASQFWDDCRKYNATVIQYIGE 314

  Fly   304 L-------------QSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNVG---- 351
            |             :..:|.|..|:.:...|.|...:..|:......|..:|     .|:|
  Rat   315 LLRYLCNTPQKPNDRDHKVKIALGNGLRGDVWREFIKRFGDIHIYEFYASTE-----GNIGFMNY 374

  Fly   352 ----GPVGCEGKVMRNVELRVLDK----------------LKMPLGINEVGIIYARLR-----FK 391
                |.||.|..:.:.|....|.|                :|:|.|  |||::..::.     |.
  Rat   375 PRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKG--EVGLLICKITELTPFFG 437

  Fly   392 WAGYYRNPE--ATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFIL 454
            :||.....|  ..|.......::|.:||:..:|.|.::|...|..|.|::....:...::.:.:.
  Rat   438 YAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVATTEVADIVG 502

  Fly   455 RLPGVSEACVFGIPDAVSTNLTACAVVRTKS-----------------PEGERLTADHIRNIVEH 502
            .:..|.|..|:|:|..........|.::.|.                 |...|.....|::.:|
  Rat   503 LVDFVEEVNVYGVPVPGHEGRIGMASIKMKENYEFNGKKLFQHISEYLPSYSRPRFLRIQDTIE- 566

  Fly   503 HLSGAYH---------------IRGGVYFIDSLPKT 523
             ::|.:.               |:..:||:|...||
  Rat   567 -ITGTFKHRKVTLMEEGFNPSVIKDTLYFMDDAEKT 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	113/556 (20%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	113/556 (20%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	113/556 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930