DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and acsf3

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	516	Identity:	109/516 - (21%)
Similarity:	219/516 - (42%)	Gaps:	91/516 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KRLGLRRGDVVG-----ISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIF 131
            |.|..:.||:.|     :.||:::|..:...:.:..||.: ||:.:.....::|:...::..::.
Zfish    93 KALTCQSGDLQGKRISFLCANDASYTVAQWASWMCGGIAV-PLYRKHPLSELEYVISDSQSSLLV 156

  Fly   132 CDVENYHIIKTVNGKLQNPA-KIYLVNGKLEGVLDISE-MLNDEDSITAAAYVPCPKLHGDHTAF 194
            ........::.:..||..|. |:...:.:.|....:.| |::|               ..:..|.
Zfish   157 AGQSFVDTLEPLAQKLGLPCLKLPATSSQFEDTQTLPEDMISD---------------WAERPAM 206

  Fly   195 IVCSSGTTGMPKGVTRSHRSLLCNCK---NPNTYTRDSVLLSFSPLY-------------WISGT 243
            ::.:|||||.||||..:|.||....:   :...:.:|.|:|...||:             |:..|
Zfish   207 LIYTSGTTGRPKGVLHTHSSLQAMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKLMCPLWVGAT 271

  Fly   244 IILLASLLNGCRRIITNRPYSVEYLLQ--LVARHKVTFLFLASHQI--ALLSKHDSDVMELKAQ- 303
            .|:|..             :|.:.:.:  :.::..:..:|:|...|  .|:..:|....:.:.|
Zfish   272 CIMLPD-------------FSAQKVWEQLICSKSPMVNVFMAVPTIYSKLIEYYDQHFTQPQVQD 323

  Fly   304 ------LQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMG-GLSKNVGGP--VGCEGK 359
                  .:.||:::...:.:.:.|..|..| |.:...:..||::|:| .||.:..||  .|..|.
Zfish   324 FIRAVCKERIRLMVSGSAALPQPVLERWAE-ITDHVLLERYGMTEIGMALSNSYKGPRVPGAVGV 387

  Fly   360 VMRNVELRVL--------------DKLKMPLGINEVGIIYARLRFKWAGYYRNPEATRRALSSDG 410
            .:..||:|::              .::|..|...| |.:..|....:..|:..|:.|..:.:.|
Zfish   388 PLPGVEVRIMMNSSIVIAEGTSKGTQVKAGLEGKE-GELLVRGSSVFQKYWNKPQETEESFTED- 450

  Fly   411 MWFRTGDIGYLDSEGYLYIQTR-DTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDAV-ST 473
            .||:|||.. |..:|..:|..| ..|:.|...::|....:|..:|..|.:::..|.|.|||. ..
Zfish   451 RWFKTGDTA-LYRDGVYWIMGRTSVDIIKSGGYKISALDVERHLLAHPDITDVAVIGAPDATWGQ 514

  Fly   474 NLTACAVVRTKSPEGERLTADHIRNIVEHHLSGAYHIRGGVYFIDSLPKTPNDKLQRRKVL 534
            .:||...:|    :|:.:....::.....|:: :|.|..|:..::.:|:....|:.::.:|
Zfish   515 KVTAVVQMR----KGKTMILSDLKAWAREHMA-SYSIPTGLILVEDMPRNQMGKVNKKDLL 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	109/516 (21%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	108/509 (21%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	108/510 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900