DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and acsl1a

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001027007.1	Gene:	acsl1a / 555308	ZFINID:	ZDB-GENE-050809-115	Length:	697	Species:	Danio rerio

Alignment Length:	545	Identity:	126/545 - (23%)
Similarity:	198/545 - (36%)	Gaps:	118/545 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FYGPEMTLGEVIMRVLQINADQVMQICDTTGQE---LTGAQLAQQSARIAQAFKRLG-LRRGD-V 81
            :|...:||.|..:|.|::..:.........||.   |:..::|.::.....|....| .:.|| .
Zfish    85 YYKDALTLYEFFLRGLRVPNNGPCLGSRKAGQPYKWLSYKEVADRAEFAGSALLHRGHSQSGDKY 149

  Fly    82 VGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGK 146
            :||.|.|....|...:|.....:...||:.....|.:.|:.|......|.||:
Zfish   150 IGIFAQNRPEWTISELACYTYSLVAVPLYDTLGTEAISYVIDKASITTIICDI------------ 202

  Fly   147 LQNPAKIYL--VNGKLEGVLDISEMLNDEDSITAAAY---------------------VPCPKLH 188
             .:.|::.|  |:|:...|..|..|.:.:..:||.|.                     .|.|...
Zfish   203 -ADKARLILDCVSGRKHSVTTIVIMESFDSELTAQAQNCGIDIISLKELEAIGKANHKTPIPPKP 266

  Fly   189 GDHTAFIVCSSGTTGMPKGVTRSHRSLLCNCKNPNTYT-------RDSVLLSFSPLY-------- 238
            .| .|.|..:|||||.|||...:|.:::.||......|       :..:.:|:.||.
Zfish   267 ED-LALICFTSGTTGNPKGAMLTHGNVVSNCSAFIKITEVHCMLNQTDIHISYLPLAHMFERVVE 330

  Fly   239 -----------WISGTIILLASLLNGCRRII------------------TNRPYSVEYLLQLVAR 274
                       :..|.|.||...|...:..|                  .|.|.. .:||.....
Zfish   331 GVLLCHGAKIGYFQGDIRLLMDDLKNLKPTIFPVVPRLLNRMFDKIFGQANTPLK-RWLLDFATS 394

  Fly   275 HKVTFLFLASHQIALLSKHDSDVM-ELKAQLQS-IRVLIGAGSKVCKAVCRRMYELIGNQRFVVG 337
            .|..  .|.|..:...|..|..:. :::|.|.. :|::|...:.|...|...:...:|.| |..|
Zfish   395 RKEA--ELKSGVVRKDSMWDKLIFSKVQASLGGRVRLMITGAAPVSPTVLTFLRAALGCQ-FYEG 456

  Fly   338 YGLSEMGG----------LSKNVGGPVGCEGKVMRNVELRVLDKLKMP-LGINEVGIIYARLRFK 391
            ||.:|...          .:.:||.|:.|.       .::::|..:|. ...|..|.:..:....
Zfish   457 YGQTECTAGCTMSLPGDWTAGHVGAPLPCN-------FVKLVDVAEMNYFAANGEGEVCVKGPNV 514

  Fly   392 WAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQ-IYPEQIEEFILR 455
            :.||.::||.|..|:...| |..|||||.....|.|.|..|...:||....: |.||:||...:|
Zfish   515 FQGYLKDPEQTSGAVDKAG-WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYIR 578

  Fly   456 LPGVSEACVFGIPDAVSTNLTACAV 480
            ...|::..|.|      .:|.||.|
Zfish   579 SDPVAQVFVHG------DSLQACLV 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	125/542 (23%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	120/529 (23%)
acsl1a	NP_001027007.1	PLN02736	88..695	CDD:178337	125/542 (23%)
acsl1a	NP_001027007.1	LC-FACS_euk	116..692	CDD:213293	119/514 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930