DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and slc27a1b

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001070716.1	Gene:	slc27a1b / 553512	ZFINID:	ZDB-GENE-061013-672	Length:	648	Species:	Danio rerio

Alignment Length:	515	Identity:	109/515 - (21%)
Similarity:	195/515 - (37%)	Gaps:	124/515 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQAFKRLGLRRGDVVGISANNSTYL 92
            |:..:..:.:.::.::...:.:::|:..:.::|.::|..:||.....|.|.||||.|...:...:
Zfish    79 TIPSLFAQRVALHPEKAALVDESSGEVWSFSELDRRSNAVAQWVLAQGWRSGDVVAIFMESRPQM 143

  Fly    93 TSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVN 157
            .::.:.....|:           |.....:::....:|.|        ..|:|...      :|.
Zfish   144 VALWLGMAKVGV-----------EPALINFNLRRDSLIHC--------MGVSGACG------MVF 183

  Fly   158 GK--LEGVLDISEMLND-------------EDSITAA---------AYVPCPKLHG---DHTAFI 195
            |.  |:.||::.|.|..             .||::||         ...|....|.   :...|.
Zfish   184 GAELLDVVLEVRESLRSLSLFSCGSAPAEMLDSLSAADLDALLSKSPETPPAVAHNKGFNDRLFY 248

  Fly   196 VCSSGTTGMPKGVTRSHRSLLCNCKNPNTYTR-------------DSVLLSFSPLYWISGTIILL 247
            :.:|||||:||.....|          :.|.|             |.|:....|||..:|.||.:
Zfish   249 IYTSGTTGLPKAAIVVH----------SRYYRIAAFSYYSFGLQPDDVVYCCLPLYHSAGNIIGV 303

  Fly   248 AS-LLNGCRRIITNRPYSVEYLLQLVARHKVTFL-FLASHQIALLSKHDSDVMELKAQLQSIRVL 310
            .. ||:|. .::..|.:|.........::..|.: ::......|||:    .:.....|..:||.
Zfish   304 GQCLLHGL-TVVIRRKFSASRFWDDCVKYNCTVVQYIGEICRYLLSQ----PVRPSESLHRVRVA 363

  Fly   311 IGAGSK--VCKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNVGGPVGCEG------------KVM 361
            :|.|.:  |.::..:|    ...:|....||.:|......|:...||..|            :::
Zfish   364 MGNGLRPNVWESFMKR----FSVKRIGEFYGATECNCSLANMDNKVGACGFNSVVLPSVYPIRLL 424

  Fly   362 RNVE-----LRVLDKLKMPLGINEVGIIYARL-------RFKWAGYYRNPEATRRALSSDGMWFR 414
            |..|     :|....|.:|....|.|||..|:       ||..   |.|.|||.:.:|.:  .||
Zfish   425 RADEDTMELIRDSRGLCVPCKPGEPGIIVGRINPQDPLRRFDG---YANEEATSKKISHN--VFR 484

  Fly   415 TGDIGY-------LDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGI 467
            .||..|       :|..||:|.:.|..|.|::....:...::|..:..|...::..|:|:
Zfish   485 KGDSAYVSGDLMVMDELGYVYFRDRGGDTFRWRGENVSTTEVEGVLSALLKQTDVAVYGV 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	109/515 (21%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	108/505 (21%)
slc27a1b	NP_001070716.1	PRK08279	60..648	CDD:236217	109/515 (21%)
slc27a1b	NP_001070716.1	AFD_class_I	103..613	CDD:302604	108/491 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930