DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and slc27a4

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001017737.1	Gene:	slc27a4 / 550432	ZFINID:	ZDB-GENE-050417-248	Length:	643	Species:	Danio rerio

Alignment Length:	497	Identity:	104/497 - (20%)
Similarity:	194/497 - (39%)	Gaps:	89/497 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQAFKRLGLRRGDVVGISANNSTYL 92
            |:.::..:.::...::...|.:.|.::.:..:|.:.|.|:|....:.|.|.||||.:...|....
Zfish    75 TVPKLFAKSVKKYGNKTALIFEGTDEKWSFKELDEYSNRVANFLLQQGFREGDVVALFMENRHQY 139

  Fly    93 TSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVN 157
            ..:.:.....|:....::.....|.:.:..:|:..|.:....|....:..|:..:....|:: |:
Zfish   140 VGLWLGMAKIGVEAALINFNLRLEALVHCVNISSAKAVVFGSELTEAMCEVHSSMGKTVKLF-VS 203

  Fly   158 GKLE------GVLDISEMLNDEDSITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSLL 216
            |:.:      |...:..:|....:|....    |........|.:.:||||||||.....|
Zfish   204 GEWDPKRVPVGTEHLDPLLETTSTIQPKQ----PDRSFTDRLFYIYTSGTTGMPKAAIVVH---- 260

  Fly   217 CNCKNPNTYTR-------------DSVLLSFSPLYWISGTIILLA-SLLNGCRRIITNRPYSVEY 267
                  :.|.|             :.||....|||..:|.|:.:. .|::| ..::..:.:|...
Zfish   261 ------SRYYRMAALVYYGFRMKPEDVLYDCLPLYHSAGNIVGIGQGLIHG-MTVVIRKKFSASK 318

  Fly   268 LLQLVARHKVTFL-FLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCRRMYELIGN 331
            ......::..|.: ::......||::...|. |.|   ..:|:.:|.|.:      :.::|...|
Zfish   319 FWDDCIKYNCTIVQYIGEICRYLLNQPRKDT-ERK---HKVRMALGNGLR------QSIWEEFTN 373

  Fly   332 QRFVVG-----YGLSEMG---GLSKNVGGPVGCEGKVM-------------RNVEL-RVLDKLKM 374
             ||.|.     ||.:|..   |...|..|..|...:::             ..:|| |..|.:.:
Zfish   374 -RFNVPQIAEFYGATECNCSLGNFDNKTGACGFNSRILPYVYPIRLVKVDEETMELIRGPDGVCI 437

  Fly   375 PLGINEVGIIYARL-------RFKWAGYYRNPEATRRALSSDGMWFRTGDIGYL-------DSEG 425
            |.|..|.|.:..|:       ||.  ||. |..||.:.::.|  .|:.||..||       |..|
Zfish   438 PCGPGEPGQLVGRIIQNDPLRRFD--GYV-NQTATNKKIAQD--VFKKGDSAYLSGDVLVMDDFG 497

  Fly   426 YLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGI 467
            |:|.:.|..|.|::....:...::|..:.||..:.:..|:|:
Zfish   498 YMYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMKDVVVYGV 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	104/497 (21%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	103/487 (21%)
slc27a4	NP_001017737.1	PRK08279	73..643	CDD:236217	104/497 (21%)
slc27a4	NP_001017737.1	hsFATP4_like	99..608	CDD:213305	101/473 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930